t-Plasminogen Activator/tPA Activity Assay Kit (Colorimetric)

Novus Biologicals | Catalog # KA0974

Novus Biologicals
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Key Product Details

Sample Type & Volume Required Per Well

Cell Culture Supernatant, Plasma, Serum (20 uL)

Sensitivity

0.034 IU/mL

Assay Range

0.039 to 40.00 IU/mL
View all t-Plasminogen Activator/tPA Activity Assays »

Product Specifications

Assay Type

Colorimetric

Kit Type

Activity Assay Kit (Colorimetric)

Species

Human

Description

Quality control test: Standard curve t-Plasminogen Activator/tPA (Human) Chromogenic Activity Assay Kit is developed to determine human PLAT activity.

Kit Contents for t-Plasminogen Activator/tPA Activity Assay Kit (Colorimetric)

  • Assay Diluent (1x): Buffered protein base
  • Human Plasminogen: Lyophilized.
  • Human tPA Standard: Human tPA (32 IU), lyophilized.
  • Microplate: A 96-well polystyrene microplate (12 strips of 8 wells).
  • Plasmin Substrate: Lyophilized.
  • Sealing Tapes: Pressure-sensitive sealing tapes that can be cut to fit the format of the individual assay.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: t-Plasminogen Activator/tPA

Tissue-type plasminogen activator (tPA) is a 68-kDa serine protease that converts the zymogen plasminogen into the active serine protease plasmin, which digests fibrin and induces the dissolution of fibrin clots. tPA is synthesized by endothelial cells in normal blood vessels and displays relatively high affinity for fibrin, suggesting that it functions predominately in physiological thrombolysis in vivo.

Long Name

Tissue Plasminogen Activator

Alternate Names

Alteplase, PLAT, Reteplase, T-PA, tPlasminogen Activator

Gene Symbol

PLAT

Additional t-Plasminogen Activator/tPA Products

Product Documents for t-Plasminogen Activator/tPA Activity Assay Kit (Colorimetric)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for t-Plasminogen Activator/tPA Activity Assay Kit (Colorimetric)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

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FAQs for t-Plasminogen Activator/tPA Activity Assay Kit (Colorimetric)

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  • Q: Please let me know the sensitivity of the tpA ELISA (Human)?

    A: For this kit, the minimum detectable dose of tPA is typically 0.08 IU/ml.

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