TCR alpha Proteins and Enzymes

T cell receptor (TCR) is a heterodimer consisting of an 945; and a 946; chain (TCR alpha/beta) or a 947; and a delta chain (TCR gamma/delta). TCR-beta is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-alpha). It is expressed on alpah/beta TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation. The MAB0872 antibody does not cross-react with delta/gamma TCR-bearing T cells.