3 results for "TGF-beta 1, 2, 3" in Products
TGF-beta 1, 2, 3 Products
TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that act as cellular switches to regulate immune function, proliferation and epithelial-mesenchymal transition.TGF-beta associates with LAP after secretion, and this complex is covalently linked to one of three latent TGF-beta binding proteins (LTBPs). TGF-beta is activated from latency by Plasmin, matrix metalloproteases, Thrombospondin 1, or a subset of integrins. TGF-beta signals through a complex of TGF-beta RII and either TGF-beta RI/ALK-5 or ALK-1. TGF-beta induced signaling is modulated by the accessory proteins Betaglycan/TGF-beta RIII and Endoglin.
| Reactivity: | Multi-Species |
| Details: | Mouse IgG1 Monoclonal Clone #1D11 |
| Applications: | WB, ELISA(Cap), B/N |
Recombinant Monoclonal Antibody.
| Reactivity: | Multi-Species |
| Details: | Mouse IgG1 Monoclonal Clone #1D11R |
| Applications: | B/N |
(Human, Mouse, Rat and Porcine). Earn double rewards for reviews
| Reactivity: | Human, Mouse, Rat, Porcine |
| Applications: |
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