TGF-beta 1, 2, 3 Antibody

Protective effect of KLF15 on vascular endothelial dysfunction induced by TNF??
Authors: B Liu, L Xu, X Yu, W Li, X Sun, S Xiao, M Guo, H Wang
Mol Med Rep, 2018;18(2):1987-1994.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

Mechanosignaling activation of TGF? maintains intervertebral disc homeostasis
Authors: Q Bian, L Ma, A Jain, JL Crane, K Kebaish, M Wan, Z Zhang, X Edward Guo, PD Sponseller, CA Séguin, LH Riley, Y Wang, X Cao
Bone Res, 2017;5(0):17008.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

A new developmental mechanism for the separation of the mammalian middle ear ossicles from the jaw
Authors: DJ Urban, N Anthwal, ZX Luo, JA Maier, A Sadier, AS Tucker, KE Sears
Proc. Biol. Sci, 2017;284(1848):.
Species: Opossum
Sample Types: In Vivo
Applications: In Vivo

Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
Authors: CJ Bohlen, FC Bennett, AF Tucker, HY Collins, SB Mulinyawe, BA Barres
Neuron, 2017;94(4):759-773.e8.
Species: Rat
Sample Types: Whole Cells
Applications: Neutralization

Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function
Authors: RM Petri, A Hackel, K Hahnel, CA Dumitru, K Bruderek, SB Flohe, A Paschen, S Lang, S Brandau
Stem Cell Reports, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

The therapeutic HIV Env C5/gp41 vaccine candidate Vacc-C5 induces specific T cell regulation in a phase I/II clinical study
Authors: K Brekke, M Sommerfelt, M Ökvist, AM Dyrhol-Rii, D Kvale
BMC Infect. Dis, 2017;17(1):228.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Granulocytic myeloid derived suppressor cells from human cord blood modulate T-helper-cell response towards an anti-inflammatory phenotype
Authors: N Köstlin, M Vogelmann, B Spring, J Schwarz, J Feucht, C Härtel, TW Orlikowsky, CF Poets, C Gille
Immunology, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

TGF-? signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes
Authors: S Khakipoor, C Ophoven, M Schrödl-Hä, M Feuerstein, B Heimrich, JW Deitmer, E Roussa
Glia, 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Neutralization

Integrin ?1 activation induces an anti-melanoma host response
Authors: L Ritsma, I Dey-Guha, N Talele, X Sole, Salony, J Chowdhury, KN Ross, S Ramaswamy
PLoS ONE, 2017;12(4):e0175300.
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay

Mesenteric lymph node stromal cell-derived extracellular vesicles contribute to peripheral de novo induction of Foxp3(+) regulatory T cells
Authors: M Pasztoi, J Pezoldt, M Beckstette, C Lipps, D Wirth, M Rohde, K Paloczi, EI Buzas, J Huehn
Eur. J. Immunol., 2017;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Histone Deacetylase (HDAC) Inhibition Induces I?B Kinase (IKK)-dependent Interleukin-8/CXCL8 Expression in Ovarian Cancer Cells
Authors: HR Gatla, Y Zou, MM Uddin, B Singha, P Bu, A Vancura, I Vancurova
J. Biol. Chem., 2017;292(12):5043-5054.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

ALS skeletal muscle shows enhanced TGF-? signaling, fibrosis and induction of fibro/adipogenic progenitor markers
Authors: D Gonzalez, O Contreras, DL Rebolledo, JP Espinoza, B van Zunder, E Brandan
PLoS ONE, 2017;12(5):e0177649.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes
Stem Cell Reports, 2016;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Sterile Inflammation Enhances ECM Degradation in Integrin ?1 KO Embryonic Skin
Cell Rep, 2016;16(12):3334-47.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC - PFA fixed

Apoptotic cell infusion treats ongoing collagen-induced arthritis, even in the presence of methotrexate, and is synergic with anti-TNF therapy
Arthritis Res Ther, 2016;18(1):184.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

K+/Cl- cotransporter KCC2 membrane trafficking and functionality is regulated by transforming growth factor beta 2
J Cell Sci, 2016;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion
PLoS ONE, 2016;11(11):e0166500.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Kluyveromyces marxianus and Saccharomyces boulardii Induce Distinct Levels of Dendritic Cell Cytokine Secretion and Significantly Different T Cell Responses In Vitro
PLoS ONE, 2016;11(11):e0167410.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Cancer associated fibroblasts regulate keratinocyte cell-cell adhesion via TGF-�-dependent pathways in genotype-specific oral cancer
Authors: S S Prime
Carcinogenesis, 2016;0(0):.
Species: Human
Sample Types: Conditioned Media
Applications: Neut

TGF-? Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions
Authors: X Chen, DL Rateri, DA Howatt, A Balakrishn, JJ Moorleghen, LA Cassis, A Daugherty
PLoS ONE, 2016;11(4):e0153811.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-? signalling
Authors: Fatemeh Mirzamoham
Nat Commun, 2016;7(0):12047.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development
Authors: H Nagashima, Y Okuyama, T Hayashi, N Ishii, T So
J Immunol, 2016;0(0):.

TGF-?1 Is Present at High Levels in Wound Fluid from Breast Cancer Patients Immediately Post-Surgery, and Is Not Increased by Intraoperative Radiation Therapy (IORT)
PLoS ONE, 2016;11(9):e0162221.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Mammary epithelial cell phagocytosis downstream of TGF-beta3 is characterized by adherens junction reorganization.
Authors: Fornetti J, Flanders K, Henson P, Tan A, Borges V, Schedin P
Cell Death Differ, 2016;23(2):185-96.
Species: Rat
Sample Types: Tissue Homogenates
Applications: Western Blot

Different tissue phagocytes sample apoptotic cells to direct distinct homeostasis programs
Nature, 2016;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury
Authors: Jeremy S Duffield
J. Clin. Invest., 2016;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

[64Cu]XYIMSR-06: A dual-motif CAIX ligand for PET imaging of clear cell renal cell carcinoma
Authors: I Minn, SM Koo, HS Lee, M Brummet, SP Rowe, MA Gorin, P Sysa-Shah, WD Lewis, HH Ahn, Y Wang, SR Banerjee, RC Mease, S Nimmagadda, ME Allaf, MG Pomper, X Yang
Oncotarget, 2016;7(35):56471-56479.
Species: Mink
Sample Types: Whole Cells
Applications: Neutralization

Mesenchymal stromal cells express GARP/LRRC32 on their surface: effects on their biology and immunomodulatory capacity.
Authors: Carrillo-Galvez A, Cobo M, Cuevas-Ocana S, Gutierrez-Guerrero A, Sanchez-Gilabert A, Bongarzone P, Garcia-Perez A, Munoz P, Benabdellah K, Toscano M, Martin F, Anderson P
Stem Cells, 2015;33(1):183-95.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

IL-10 inhibits neuraminidase-activated TGF-beta and facilitates Th1 phenotype during early phase of infection.
Authors: Dutta A, Huang C, Chen T, Lin C, Chiu C, Lin Y, Chang C, He Y
Nat Commun, 2015;6(0):6374.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

STAT6-Dependent Collagen Synthesis in Human Fibroblasts Is Induced by Bovine Milk.
Authors: Kippenberger S, Zoller N, Kleemann J, Muller J, Kaufmann R, Hofmann M, Bernd A, Meissner M, Valesky E
PLoS ONE, 2015;10(7):e0131783.
Species: Bovine
Sample Types: Milk
Applications: Neutralization

Bortezomib inhibits expression of TGF-beta1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells.
Authors: Chang T, Poltoratsky V, Vancurova I
J Immunol, 2015;194(6):2942-53.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Ex vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory T cell-specific demethylated region.
Authors: Rossetti M, Spreafico R, Saidin S, Chua C, Moshref M, Leong J, Tan Y, Thumboo J, van Loosdregt J, Albani S
J Immunol, 2015;194(1):113-24.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-beta.
Authors: Ungefroren H, Hyder A, Hinz H, Groth S, Lange H, El-Sayed K, Ehnert S, Nussler A, Fandrich F, Gieseler F
PLoS ONE, 2015;10(2):e0118097.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-beta Signaling in the Retinal Pigment Epithelium.
Authors: Li Y, Song D, Song Y, Zhao L, Wolkow N, Tobias J, Song W, Dunaief J
J Biol Chem, 2015;290(19):11918-34.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-beta (TGF-beta) Activation and Fibroblast Differentiation.
Authors: Dayer C, Stamenkovic I
J Biol Chem, 2015;290(22):13763-78.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4+ T cells.
Authors: Schmetterer K, Neunkirchner A, Wojta-Stremayr D, Leitner J, Steinberger P, Pickl W
FASEB J, 2015;29(3):759-71.
Species: Human
Sample Types: Whole Cells
Applications: Blocking

Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition.
Authors: Mizuuchi Y, Aishima S, Ohuchida K, Shindo K, Fujino M, Hattori M, Miyazaki T, Mizumoto K, Tanaka M, Oda Y
Lab Invest, 2015;95(2):193-206.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-beta.
Authors: Pieters B, Arntz O, Bennink M, Broeren M, van Caam A, Koenders M, van Lent P, van den Berg W, de Vries M, van der Kraan P, van de Loo F
PLoS ONE, 2015;10(3):e0121123.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

CD4(+) NKG2D(+) T cells induce NKG2D down-regulation in natural killer cells in CD86-RAE-1epsilon transgenic mice.
Authors: Lin Z, Wang C, Xia H, Liu W, Xiao W, Qian L, Jia X, Ding Y, Ji M, Gong W
Immunology, 2014;141(3):401-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Functional effects of TGF-beta1 on mesenchymal stem cell mobilization in cockroach allergen-induced asthma.
Authors: Gao P, Zhou Y, Xian L, Li C, Xu T, Plunkett B, Huang S, Wan M, Cao X
J Immunol, 2014;192(10):4560-70.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Biglycan and decorin differentially regulate signaling in the fetal membranes.
Authors: Wu Z, Horgan C, Carr O, Owens R, Iozzo R, Lechner B
Matrix Biol, 2014;35(0):266-75.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot

The extracellular matrix protein MAGP1 supports thermogenesis and protects against obesity and diabetes through regulation of TGF-beta.
Authors: Craft C, Pietka T, Schappe T, Coleman T, Combs M, Klein S, Abumrad N, Mecham R
Diabetes, 2014;63(6):1920-32.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Angiotensin II-dependent TGF-beta signaling contributes to Loeys-Dietz syndrome vascular pathogenesis.
Authors: Gallo E, Loch D, Habashi J, Calderon J, Chen Y, Bedja D, van Erp C, Gerber E, Parker S, Sauls K, Judge D, Cooke S, Lindsay M, Rouf R, Myers L, ap Rhys C, Kent K, Norris R, Huso D, Dietz H
J Clin Invest, 2014;124(1):448-60.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Aminobisphosphonates prevent the inhibitory effects exerted by lymph node stromal cells on anti-tumor Vdelta 2 T lymphocytes in non-Hodgkin lymphomas.
Authors: Musso A, Catellani S, Canevali P, Tavella S, Vene R, Boero S, Pierri I, Gobbi M, Kunkl A, Ravetti J, Zocchi M, Poggi A
Haematologica, 2014;99(1):131-9.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Influenza promotes collagen deposition via alphavbeta6 integrin-mediated transforming growth factor beta activation.
Authors: Jolly L, Stavrou A, Vanderstoken G, Meliopoulos V, Habgood A, Tatler A, Porte J, Knox A, Weinreb P, Violette S, Hussell T, Kolb M, Stampfli M, Schultz-Cherry S, Jenkins G
J Biol Chem, 2014;289(51):35246-63.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6.
Authors: Nagashima, Hiroyuki, Okuyama, Yuko, Asao, Atsuko, Kawabe, Takeshi, Yamaki, Satoshi, Nakano, Hiroyasu, Croft, Michael, Ishii, Naoto, So, Takanori
Nat Immunol, 2014;15(5):449-56.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Tumor necrosis factor-related apoptosis-inducing ligand mediates the resolution of allergic airway inflammation induced by chronic allergen inhalation.
Authors: Faustino L, Fonseca D, Florsheim E, Resende R, Lepique A, Faquim-Mauro E, Gomes E, Silva J, Yagita H, Russo M
Mucosal Immunol, 2014;7(5):1199-208.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome.
Authors: Cook J, Carta L, Benard L, Chemaly E, Chiu E, Rao S, Hampton T, Yurchenco P, Costa K, Hajjar R, Ramirez F
J Clin Invest, 2014;124(3):1329-39.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-beta.
Authors: Alcaraz L, Exposito J, Chuvin N, Pommier R, Cluzel C, Martel S, Sentis S, Bartholin L, Lethias C, Valcourt U
J Cell Biol, 2014;205(3):409-28.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Senescent cancer-associated fibroblasts secrete active MMP-2 that promotes keratinocyte dis-cohesion and invasion.
Authors: Hassona Y, Cirillo N, Heesom K, Parkinson E, Prime S
Br J Cancer, 2014;111(6):1230-7.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Neutralization

Basal localization of MT1-MMP is essential for epithelial cell morphogenesis in 3D collagen matrix.
Authors: Weaver S, Wolters B, Ito N, Woskowicz A, Kaneko K, Shitomi Y, Seiki M, Itoh Y
J Cell Sci, 2014;127(0):1203-13.
Species: Canine
Sample Types: Whole Cells
Applications: Neutralization

Bovine gammadelta T cells are a major regulatory T cell subset.
Authors: Guzman E, Hope J, Taylor G, Smith A, Cubillos-Zapata C, Charleston B
J Immunol, 2014;193(1):208-22.
Species: Bovine
Sample Types: Whole Cells
Applications: Bioassay

CD2-mediated regulation of peripheral CD4(+) CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim.
Authors: Kashiwakura Y, Sakurai D, Kanno Y, Hashiguchi M, Kobayashi A, Kurosu A, Tokudome S, Kobata T, Kojima H
Immunology, 2013;139(1):48-60.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

A dynamic dual role of IL-2 signaling in the two-step differentiation process of adaptive regulatory T cells.
Authors: Guo Z, Khattar M, Schroder P, Miyahara Y, Wang G, He X, Chen W, Stepkowski S
J Immunol, 2013;190(7):3153-62.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Human CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal effector T cells via the cytokine TGF-beta.
Authors: Yu C, Becker C, Wang Y, Marches F, Helft J, Leboeuf M, Anguiano E, Pourpe S, Goller K, Pascual V, Banchereau J, Merad M, Palucka K
Immunity, 2013;38(4):818-30.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Dendritic cell-derived thrombospondin-1 is critical for the generation of the ocular surface Th17 response to desiccating stress.
Authors: Gandhi N, Su Z, Zhang X, Volpe E, Pelegrino F, Rahman S, Li D, Pflugfelder S, de Paiva C
J Leukoc Biol, 2013;94(6):1293-301.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization

TGF-beta signaling regulates neuronal C1q expression and developmental synaptic refinement.
Authors: Bialas A, Stevens B
Nat Neurosci, 2013;16(12):1773-82.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Immunodepletion

Chronic but not acute virus infection induces sustained expansion of myeloid suppressor cell numbers that inhibit viral-specific T cell immunity.
Authors: Norris B, Uebelhoer L, Nakaya H, Price A, Grakoui A, Pulendran B
Immunity, 2013;38(2):309-21.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Staphylococcus aureus phenol-soluble modulin peptides modulate dendritic cell functions and increase in vitro priming of regulatory T cells.
Authors: Schreiner J, Kretschmer D, Klenk J, Otto M, Buhring H, Stevanovic S, Wang J, Beer-Hammer S, Peschel A, Autenrieth S
J Immunol, 2013;190(7):3417-26.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

The metalloprotease ADAM12 regulates the effector function of human Th17 cells.
Authors: Zhou A, El Hed A, Mercer F, Kozhaya L, Unutmaz D
PLoS ONE, 2013;8(11):e81146.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Peyer's patch inducer cells play a leading role in the formation of B and T cell zone architecture.
Authors: Nakagawa R, Togawa A, Nagasawa T, Nishikawa S
J Immunol, 2013;190(7):3309-18.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta.
Authors: Zielinski CE, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, Monticelli S, Lanzavecchia A, Sallusto F
Nature, 2012;484(7395):514-8.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

TGF-beta signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation.
Authors: Zhang N, Bevan MJ
Nat. Immunol., 2012;13(7):667-73.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets.
Authors: Montane J, Bischoff L, Soukhatcheva G, Dai DL, Hardenberg G, Levings MK, Orban PC, Kieffer TJ, Tan R, Verchere CB
J. Clin. Invest., 2011;121(0):3024.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.
Authors: Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, Morris M, Wyatt L, Farshid G, Lim YY, Lindeman GJ, Shannon MF, Drew PA, Khew-Goodall Y, Goodall GJ
Mol. Biol. Cell, 2011;22(10):1686-98.
Species: Canine
Sample Types: Whole Cells
Applications: Neutralization

Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease.
Authors: Ma W, Han W, Greer PA, Tuder RM, Toque HA, Wang KK, Caldwell RW, Su Y
J. Clin. Invest., 2011;121(11):4548-66.
Species: Human
Sample Types: Whole Cells
Applications: ICC

Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance.
Authors: Chaturvedi V, Collison LW, Guy CS, Workman CJ, Vignali DA
J. Immunol., 2011;186(12):6661-6.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Anti-Asthma Simplified Herbal Medicine Intervention-induced long-lasting tolerance to allergen exposure in an asthma model is interferon-gamma, but not transforming growth factor-beta dependent.
Authors: Srivastava K, Zhang T, Yang N, Sampson H, Li XM
Clin. Exp. Allergy, 2010;40(11):1678-88.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior.
Authors: Koo JW, Russo SJ, Ferguson D, Nestler EJ, Duman RS
Proc. Natl. Acad. Sci. U.S.A., 2010;107(6):2669-74.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Interleukin-17-producing gammadelta+ T cells protect NOD mice from type 1 diabetes through a mechanism involving transforming growth factor-beta.
Authors: Han G, Wang R, Chen G
Immunology, 2010;129(2):197-206.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells.
Authors: Tso GH, Law HK, Tu W
Stem Cells, 2010;28(5):939-54.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
J. Invest. Dermatol., 2010;130(3):866-75.
Species: Mouse
Sample Types: Cell Lysates
Applications: Bioassay

Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade.
Authors: Lu H, Wagner WM, Gad E, Yang Y, Duan H, Amon LM, Van Denend N, Larson ER, Chang A, Tufvesson H, Disis ML
J. Immunol., 2010;184(9):5360-7.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10.
Authors: Ilarregui JM, Croci DO, Bianco GA, Toscano MA, Salatino M, Vermeulen ME, Geffner JR, Rabinovich GA
Nat. Immunol., 2009;10(9):981-91.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Fractional CO2 laser: a novel therapeutic device upon photobiomodulation of tissue remodeling and cytokine pathway of tissue repair.
Authors: Prignano F, Campolmi P, Bonan P
Dermatol Ther, 2009;22(0):S8-15.
Species: Human
Sample Types: Whole Tissue
Applications: IHC

TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23.
Authors: Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M
Eur. J. Immunol., 2009;39(5):1221-30.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

The AP-1 transcription factor Batf controls T(H)17 differentiation.
Authors: Schraml BU, Hildner K, Ise W, Lee WL, Smith WA, Solomon B, Sahota G, Sim J, Mukasa R, Cemerski S, Hatton RD, Stormo GD, Weaver CT, Russell JH, Murphy TL, Murphy KM
Nature, 2009;460(7253):405-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Loss of Thy-1 inhibits alveolar development in the newborn mouse lung.
Authors: Nicola T, Hagood JS, James ML, Macewen MW, Williams TA, Hewitt MM, Schwiebert L, Bulger A, Oparil S, Chen YF, Ambalavanan N
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(5):L738-50.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.
Authors: Han Y, Guo Q, Zhang M, Chen Z, Cao X
J. Immunol., 2009;182(1):111-20.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function.
Authors: Tran DQ, Glass DD, Uzel G, Darnell DA, Spalding C, Holland SM, Shevach EM
J. Immunol., 2009;182(5):2929-38.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Characterization of naturally occurring CD4+CD25+ regulatory T cells in rhesus monkeys.
Authors: Haanstra KG, van der Maas MJ, 't Hart BA, Jonker M
Transplantation, 2008;85(8):1185-92.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Neutralization

Circulating myeloid dendritic cells of advanced cancer patients result in reduced activation and a biased cytokine profile in invariant NKT cells.
Authors: van der Vliet HJ, Wang R, Yue SC, Koon HB, Balk SP, Exley MA
J. Immunol., 2008;180(11):7287-93.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production.
Authors: Tabata T, Kawakatsu H, Maidji E, Sakai T, Sakai K, Fang-Hoover J, Aiba M, Sheppard D, Pereira L
Am. J. Pathol., 2008;172(4):1127-40.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells.
Authors: Terme M, Chaput N, Combadiere B, Ma A, Ohteki T, Zitvogel L
J. Immunol., 2008;180(7):4679-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling.
Authors: Pen A, Moreno MJ, Durocher Y, Deb-Rinker P, Stanimirovic DB
Oncogene, 2008;27(54):6834-44.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells.
Authors: Perruche S, Zhang P, Liu Y, Saas P, Bluestone JA, Chen W
Nat. Med., 2008;14(5):528-35.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells.
Authors: Carlson ME, Hsu M, Conboy IM
Nature, 2008;454(7203):528-32.
Species: Mouse
Sample Types: Whole Tissue
Applications: Neutralization

Molecular mechanisms of TGFbeta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.
Authors: Akool el-S, Doller A, Babelova A, Tsalastra W, Moreth K, Schaefer L, Pfeilschifter J, Eberhardt W
J. Immunol., 2008;181(4):2831-45.
Species: Rat
Sample Types: In Vivo
Applications: In vivo

Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge.
Authors: He R, Oyoshi MK, Jin H, Geha RS
Proc. Natl. Acad. Sci. U.S.A., 2007;104(40):15817-22.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid.
Authors: Saurer L, McCullough KC, Summerfield A
J. Immunol., 2007;179(6):3504-14.
Species: Porcine
Sample Types: Cell Culture Supernates
Applications: ELISA Development

Hepatitis C virus (HCV)-specific CD8+ cells produce transforming growth factor beta that can suppress HCV-specific T-cell responses.
Authors: Alatrakchi N, Graham CS, van der Vliet HJ, Sherman KE, Exley MA, Koziel MJ
J. Virol., 2007;81(11):5882-92.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes.
Authors: Lamar JM, Iyer V, DiPersio CM
J. Invest. Dermatol., 2007;128(3):575-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
Authors: Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM
Blood, 2007;109(10):4272-9.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Luminex Development

Innate immune responses to herpes simplex virus type 2 influence skin homing molecule expression by memory CD4+ lymphocytes.
Authors: Koelle DM, Huang J, Hensel MT, McClurkan CL
J. Virol., 2006;80(6):2863-72.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Requirement of Smad3 for mast cell growth.
Authors: Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H
Cell. Immunol., 2006;240(1):47-52.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Long-term staphylococcal enterotoxin C1 exposure induces soluble factor-mediated immunosuppression by bovine CD4+ and CD8+ T cells.
Authors: Seo KS, Lee SU, Park YH, Davis WC, Fox LK, Bohach GA
Infect. Immun., 2006;75(1):260-9.
Species: Bovine
Sample Types: Whole Cells
Applications: Neutralization

Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells.
Authors: Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW, Chatterjee SK
J. Cell. Biochem., 2006;97(5):1036-51.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC Frozen

Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction.
Authors: Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S
Gut, 2006;56(2):243-52.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure.
Authors: Neurohr C, Nishimura SL, Sheppard D
Am. J. Respir. Cell Mol. Biol., 2006;35(2):252-9.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct.
Authors: Maeshima A, Vaughn DA, Choi Y, Nigam SK
Dev. Biol., 2006;295(2):473-85.
Species: Rat
Sample Types: Whole Tissue
Applications: Neutralization

IGF-I and IGFBP-3 augment transforming growth factor-beta actions in human renal carcinoma cells.
Authors: Rosendahl AH, Forsberg G
Kidney Int., 2006;70(9):1584-90.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Transforming growth factor beta1 regulates follistatin mRNA expression during in vitro bovine granulosa cell differentiation.
Authors: Fazzini M, Vallejo G, Colman-Lerner A, Trigo R, Campo S, Baranao JL, Saragueta PE
J. Cell. Physiol., 2006;207(1):40-8.
Species: Bovine
Sample Types: Whole Cells
Applications: Neutralization

Retinal neurons regulate proliferation of postnatal progenitors and Muller glia in the rat retina via TGF beta signaling.
Authors: Close JL, Gumuscu B, Reh TA
Development, 2005;132(13):3015-26.
Species: Rat
Sample Types: In Vivo
Applications: In vivo

Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function.
Authors: Godfrey WR, Spoden DJ, Ge YG, Baker SR, Liu B, Levine BL, June CH, Blazar BR, Porter SB
Blood, 2005;105(2):750-8.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Neutralization

Protection against autoimmunity in nonlymphopenic hosts by CD4+ CD25+ regulatory T cells is antigen-specific and requires IL-10 and TGF-beta.
Authors: Huang X, Zhu J, Yang Y
J. Immunol., 2005;175(7):4283-91.
Species: Mouse
Sample Types:
Applications: Neutralization

P311 binds to the latency associated protein and downregulates the expression of TGF-beta1 and TGF-beta2.
Authors: Paliwal S, Shi J, Dhru U, Zhou Y, Schuger L
Biochem. Biophys. Res. Commun., 2004;315(4):1104-9.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures.
Authors: Godfrey WR, Ge YG, Spoden DJ, Levine BL, June CH, Blazar BR, Porter SB
Blood, 2004;104(2):453-61.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
Authors: Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
Immunology, 2004;112(2):274-89.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice.
Authors: Kitani A, Fuss I, Pedersen A, Nawata H
J. Immunol., 2004;172(2):834-42.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Authors: Torrealba JR, Katayama M, Fechner JH, Jankowska-Gan E, Kusaka S, Schultz JM, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
J. Immunol., 2004;172(9):5753-64.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Tissue Homogenates
Applications: Western Blot

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3.
Authors: Chen, WanJun, Jin, Wenwen, Hardegen, Neil, Lei, Ke-Jian, Li, Li, Marinos, Nancy, McGrady, George, Wahl, Sharon M
J Exp Med, 2003;198(12):1875-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization

Immunosuppression in hamsters with progressive visceral leishmaniasis is associated with an impairment of protein kinase C activity in their lymphocytes that can be partially reversed by okadaic acid or anti-transforming growth factor beta antibody.
Authors: Mookerjee A, Sen PC, Ghose AC
Infect. Immun., 2003;71(5):2439-46.
Species: Hamster
Sample Types: Whole Cells
Applications: Neutralization

IL-15 and cognate antigen successfully expand de novo-induced human antigen-specific regulatory CD4+ T cells that require antigen-specific activation for suppression.
Authors: Koenen HJ, Fasse E, Joosten I
J. Immunol., 2003;171(12):6431-41.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

Marked airway eosinophilia prevents development of airway hyper-responsiveness during an allergic response in IL-5 transgenic mice.
Authors: Kobayashi T, Iijima K, Kita H
J. Immunol., 2003;170(11):5756-63.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo

The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure.
Authors: Feugate JE, Li Q, Wong L, Martins-Green M
J. Cell Biol., 2002;156(1):161-72.
Species: Chicken
Sample Types: Whole Cells
Applications: Neutralization

Human macrophages induce CD4(+)Foxp3(+) regulatory T cells via binding and re-release of TGF-beta.
Authors: Schmidt A, Zhang X, Joshi R, Iqbal S, Wahlund C, Gabrielsson S, Harris R, Tegner J
Immunol Cell Biol, 0;94(8):747-62.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization

PARP-1 regulates expression of TGF-beta receptors in T cells.
Authors: Zhang P, Nakatsukasa H, Tu E, Kasagi S, Cui K, Ishikawa M, Konkel J, Maruyama T, Wei G, Abbatiello B, Wang Z, Zhao K, Chen W
Blood, 0;122(13):2224-32.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

Commercially Available Preparations of Recombinant Wnt3a Contain Non-Wnt Related Activities Which May Activate TGF-beta Signaling.
Authors: Carthy J, Engstrom U, Heldin C, Moustakas A
J Cell Biochem, 0;117(4):938-45.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A mechanism linking Id2-TGFbeta crosstalk to reversible adaptive plasticity in neuroblastoma.
Authors: Chakrabarti L, Wang B, Lee N, Sandler A
PLoS ONE, 0;8(12):e83521.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: Western Blot