1 result for "VMAT1/SLC18A1 Fluorescent Probes and Dyes" in Products

VMAT1/SLC18A1 Fluorescent Probes and Dyes

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM]

Selective fluorescent substrate of DAT and VMAT2

Chemical Name: 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one methanesulfonate
Purity: ≥98%
Selective fluorescent substrate of DAT and VMAT2
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