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3 results for "XIAP" in Products
XIAP Products
XIAP (X-linked inhibitor of apoptosis) is a member of the Inhibitor of Apoptosis (IAP) protein family. XIAP inhibits the activity of caspase-3, -7, and -9. Caspase inhibition is reversed when SMAC/Diablo or HtrA2/Omi directly binds the BIR domain of XIAP.
Dimeric Smac mimetic; potent IAP inhibitor
| Chemical Name: | 3,3'-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolinamide |
| Purity: | ≥97% |
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High affinity XIAP antagonist; active in vivo
| Chemical Name: | N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride |
| Purity: | ≥98% |
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Potent Lys-covalent pan-IAP inhibitor
| Chemical Name: | (R)-1-((S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidine-2-carboxamido)-2,3-dihydro-1H-inden-4-yl sulfurofluoridate |
| Purity: | ≥95% |
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