(R)-(+)-8-Hydroxy-DPAT hydrobromide

Tocris Bioscience | Catalog # 1080

Selective 5-HT1A agonist; enantiomer of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529)
Tocris Bioscience
Discontinued Product
1080 has been discontinued. View all 5-HT1 Receptor Agonists products.

Key Product Details

Description

Selective 5-HT1A agonist; enantiomer of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529)
View all 5-HT1 Receptor Agonists »

Product Description

(R)-(+)-8-Hydroxy-DPAT hydrobromide is a full 5-HT1A serotonin receptor agonist. Reduces hippocampal 5-HT levels following systemic administration in rats in vivo. More active enantiomer of 8-Hydroxy-DPAT hydrobromide.

Racemate and 7-Hydroxy Isomer also available.

Product Specifications for (R)-(+)-8-Hydroxy-DPAT hydrobromide

Molecular Weight

328.29

Formula

C16H25NO.HBr

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

(2R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide

CAS Number

78095-19-9

PubChem ID

11957570

InChI Key

BATPBOZTBNNDLN-PFEQFJNWSA-N

SMILES

Br.CCCN(CCC)[C@@H]1CCC2=CC=CC(O)=C2C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 24.62 75
DMSO 24.62 75

Preparing Stock Solutions for (R)-(+)-8-Hydroxy-DPAT hydrobromide

The following data is based on the product molecular weight 328.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 4.06 mL 20.31 mL 40.61 mL
3.75 mM 0.81 mL 4.06 mL 8.12 mL
7.5 mM 0.41 mL 2.03 mL 4.06 mL
37.5 mM 0.08 mL 0.41 mL 0.81 mL

Calculators

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Product Documents for (R)-(+)-8-Hydroxy-DPAT hydrobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (R)-(+)-8-Hydroxy-DPAT hydrobromide

For research use only

Citations for (R)-(+)-8-Hydroxy-DPAT hydrobromide

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  • The 5,760 bioactive compound library is a collated compound set of approved drugs and biologically active compound
    Name: Anonymous
    Species: C. albicans
    Assay Type: In Vitro
    Verified Customer | Posted 02/01/2020
    Biologically active compounds that have been documented to interact with a wide range of targets including SB-224289 (Cat. # 1221), MG-624 (Cat. # 1356), GVIA (Cat. No. 1085), DPAT hydrobromide (Cat. No. 1080) and valinomycin (VA; Cat. # 3373) were ordered from Tocris Bioscience
    (R)-(+)-8-Hydroxy-DPAT hydrobromide 1080

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