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CCL3/MIP-1 alpha Antibody Pair [Biotin]

Name: CCL3/MIP-1 alpha Antibody Pair [Biotin]
Brand: Novus Biologicals
SKU: NBP3-57751
Price: 899 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-57751

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Product Specifications
Scientific Data
Kit Contents
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Assay Type

Sandwich ELISA

Sample Type

Cell culture supernatants from cats (Felis catus). Additional biological sample types reported in the literature, including serum, plasma, peripheral blood mononuclear cell (PBMC) culture supernatants, bronchoalveolar lavage fluid, and tissue lysates. (100 ul)

Reactivity

Feline

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Product Specifications

Description

Contains a capture antibody, detection antibody, and recombinant protein standard for assay development. These antibodies have been validated to function together in an ELISA format using the provided standard. Optimal buffers, antibody concentrations, incubation times, temperatures, and assay conditions have not been predetermined, allowing researchers to optimize assay sensitivity and dynamic range based on their specific sample type and experimental requirements. The quantities of components are not matched, and individual components may be purchased separately. This product is for research use only.

Sample Volume Required

100 ul

Conjugate

Biotin

Scientific Data Images for CCL3/MIP-1 alpha Antibody Pair [Biotin]

ELISA: CCL3/MIP-1 alpha Antibody Pair [Biotin] [NBP3-57751] -

Representative standard curve for CCL3/MIP-1 alpha Antibody Pair [Biotin] (NBP3-57751)

Kit Contents for CCL3/MIP-1 alpha Antibody Pair [Biotin]

Capture Antibody (1 Set = <= 10 Plates; 2 Set = <= 20 Plates): (Catalog # <a href= /products/ccl3-mip-1-alpha-antibody_nbp3-57653 >NBP3-57653</a>)
Detection Antibody (Biotinylated): (Catalog # <a href= "/products/ccl3-mip-1-alpha-antibody_nbp3-57684" >NBP3-57684</a>)
Standard: (Catalog # <a href= "/products/ccl3-mip-1-alpha-antibody_nbp3-57485" >NBP3-57485</a>)

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: CCL3/MIP-1 alpha

CCL3/MIP-1 alpha, is a beta chemokine that can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. It forms complexes with sulfated proteoglycans and also associates into noncovalently-linked dimers and high molecular weight polymers. These complexes of CCL3 are protected from proteolytic digestion by insulin degrading enzyme (IDE) which can cleave the monomeric chemokine. CCL3 signals through CCR1, CCR3, and CCR5, and it is internalized by the decoy chemokine receptor D6. CCL3 promotes the chemoattraction, adhesion to activated vascular endothelium, and cellular activation of many hematopoietic cell types. It can promote tumor metastasis, hyperalgesia, and inflammation and suppress HIV replication and hematopoietic stem cell proliferation.

Alternate Names

G0S19-1, LD78a, MIP-1 alpha, MIP1 alpha, MIP1A, PAT 464.1, SCYA3, SIS-beta

Gene Symbol

CCL3

Additional CCL3/MIP-1 alpha Products

Product Documents for CCL3/MIP-1 alpha Antibody Pair [Biotin]

Download Product Datasheets

Download Manual - NBP3-57751

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CCL3/MIP-1 alpha Antibody Pair [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.