Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot, Immunocytochemistry

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Rat IgG2A Clone # 477226
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Product Specifications

Immunogen

E. coli-derived recombinant mouse Cited-2
Met1-Cys269
Accession # O35740

Specificity

Detects human Cited-2 in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Cited-2 Antibody (477226) [FITC]

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Cited-2

CITED2 is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator. CITED-2 has been proposed as a negative regulator for HIF-1 alpha, as it is thought to interfere with the binding of transcription factors HIF-1a and STAT2 to p300/CBP. Recruitment of CBP/p300 by HIF-1 is essential for the transcriptional response to hypoxia.

CITED 2 antibodies are useful tools for research on hypoxic response mechanisms.

Long Name

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Alternate Names

Cited2, MRG-1, MSG-related protein 1, P35srj

Gene Symbol

CITED2

Additional Cited-2 Products

Product Documents for Cited-2 Antibody (477226) [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cited-2 Antibody (477226) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

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Associated Pathways

HIF Repressor Pathways HIF Repressor Pathway Thumbnail