Human IFN-alpha 6/IFNA6 Antibody (1009720)

R&D Systems | Catalog # MAB10212

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 1009720
View all IFN-alpha 6/IFNA6 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human IFN-alpha 6/IFNA6
Leu28-Lys207
Accession # Q90W0

Specificity

Detects human IFN-alpha 6/IFNA6 in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Human IFN-alpha 6/IFNA6 Antibody (1009720)

Detection of Human IFN-alpha 6/IFNA6 antibody by Western Blot.

Detection of Human IFN-alpha 6/IFNA6 by Western Blot.

Western blot shows lysates of HEK001 human epidermal keratinocyte cell line and NHEK human normal epidermal keratinocytes. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human IFN-alpha 6/IFNA6 Monoclonal Antibody (Catalog # MAB10212) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for IFN-alpha 6/IFNA6 at approximately 26 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Applications for Human IFN-alpha 6/IFNA6 Antibody (1009720)

Application
Recommended Usage

Western Blot

2 µg/mL
Sample: HEK001 human epidermal keratinocyte cell line and NHEK human normal epidermal keratinocytes

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background: IFN-alpha 6/IFNA6

Interferon kappa, also known as IFN-kappa, is a 207 aminoacids protein that in humans is encoded by the IFNK gene. IFN-kappa is a member of the type I interferon family which also includes IFN-alpha, -beta, -epsilon, and -omega. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. Human IFN-kappa has been detected in keratinocytes, monocytes, and monocyte-derived dendritic cells and is reported to have contact-dependent antiviral activity. Human papillomavirus (HPV) 16 oncogene expression, which is necessary for the development of cervical cancer, has been shown to down-regulate human IFN-kappa expression.

Long Name

Interferon alpha 6

Alternate Names

IFN-alpha K, IFNA6, IFNalpha K

Entrez Gene IDs

3443 (Human); 15969 (Mouse)

Gene Symbol

IFNA6

UniProt

Q90W0

Additional IFN-alpha 6/IFNA6 Products

Product Documents for Human IFN-alpha 6/IFNA6 Antibody (1009720)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human IFN-alpha 6/IFNA6 Antibody (1009720)

For research use only

Related Research Areas

Interferons

Customer Reviews for Human IFN-alpha 6/IFNA6 Antibody (1009720)

There are currently no reviews for this product. Be the first to review Human IFN-alpha 6/IFNA6 Antibody (1009720) and earn rewards!

Have you used Human IFN-alpha 6/IFNA6 Antibody (1009720)?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 for a review with an image

$10/€7/£6/$10CAN/¥1110 for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies