Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.
Human IFN-alpha Antibody (MMHA-13)
R&D Systems | Catalog # 21116-1
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Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Direct ELISA
Cited:
Neutralization, Blocking
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # MMHA-13
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Product Specifications
Immunogen
Human Leukocyte Interferon
Specificity
Detects human interferon alpha in direct ELISAs.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Human IFN-alpha Antibody (MMHA-13)
Application
Recommended Usage
Direct ELISA
Binds to human interferon beta with high affinity.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Phosphate-buffered saline (PBS) containing 0.1% bovine serum albumin (BSA)
Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
After receipt, the product may be stored at -20°C for short-term use (
≤ 6 months). For
long-term storage, we recommend storing the product at -70°C or below for retention of full activity. When thawing, the
contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing
should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers
containing protein such as 0.1% bovine serum albumin (BSA).
Background: IFN-alpha
Long Name
Interferon alpha
Alternate Names
IFNalpha, LeIF D
Entrez Gene IDs
3440 (Human)
Gene Symbol
IFNA2
Additional IFN-alpha Products
Product Documents for Human IFN-alpha Antibody (MMHA-13)
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human IFN-alpha Antibody (MMHA-13)
For research use only
Citations for Human IFN-alpha Antibody (MMHA-13)
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