Human IL-5 Luminex Performance Assay

Name: Human IL-5 Luminex Performance Assay
Brand: R&D Systems
SKU: LUH205

Catalog #: LUH205 Datasheet / COA / SDS

Discontinued Product

LUH205 has been discontinued and is replaced by LUHM205.

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Citations (15)

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Human IL-5 Luminex Performance Assay Summary

Assay Type	bead-based multiplex assay for the Luminex^® platform
Format	1 x 96-well microplate and antibody-coated beads
Analytes Detected	Please see analyte list in assay customization tool below.
Performance Validation	Luminex Assays are validated for use with cell culture supernatants, plasma and serum. All Luminex assays are tested for sensitivity, intra-assay precision, inter-assay precision and to ensure assay linearity for validated sample types. Antibody pairs are selected and tested to confirm the parallel detection of natural and recombinant standard protein and to ensure the accurate determination of target analytes within biological samples. Assays for each target analyte are screened against all target analytes to confirm low antibody cross-reactivity.

Not finding your analyte of interest? View our complete Luminex offering in the full version of our Luminex Assay Customization Tool. We also offer Custom Luminex Services.

Which Luminex Assay is right for me?

Assays for the Luminex platform are offered as High Performance Assays or Assays. The Luminex High Performance Assays are fully validated panels with a focused selection of analytes. They are available in We Mix, You Mix, and Predetermined formats. The Luminex Assays allows for the maximum number of analytes in a multiplex and is supplied as a premixed kit. View a table comparing the features and benefits of these bead-based multiplex assays.

Background: IL-5

IL-5 (Interleukin-5) is a secreted cytokine that is expressed as a covalent dimer. It is produced by activated Th2 cells, eosinophils, mast cells, and iNKT cells and promotes eosinophilic and basophilic differentiation and activation. IL-5 signals through a receptor complex containing IL-5 R alpha and the Common beta Chain/CD131 on eosinophils and basophils. Naturally occurring soluble forms of IL-5 R alpha retain the ability to bind IL-5 and limit its bioavailability.

Long Name

Interleukin 5

Entrez Gene IDs

3567 (Human); 16191 (Mouse); 24497 (Rat); 397409 (Porcine); 280825 (Bovine); 403790 (Canine); 100034199 (Equine); 493803 (Feline)

Alternate Names

BCDF mu; B-cell differentiation factor I; BCGFII; EDF; Eo-CSF; Eosinophil differentiation factor; IL5; IL-5; IL-5T-cell replacing factor; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; TRF; TRFB cell differentiation factor I

Product Datasheets

COA

SDS

Product Specific Notices

Luminex® is a registered trademark of Luminex Corporation.

Citations for Human IL-5 Luminex Performance Assay

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

15 Citations: Showing 1 - 10
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Association of Mucosal Organisms with Patterns of Inflammation in Chronic Rhinosinusitis.
Authors: Chalermwatanachai T, Zhang N, Holtappels G, Bachert C
PLoS ONE, 2015-08-14;10(8):e0136068.
Species: Human
Sample Types: Tissue Homogenates
Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue.
Authors: Beck I, Van Crombruggen K, Holtappels G, Daubeuf F, Frossard N, Bachert C, De Bosscher K
PLoS ONE, 2015-04-13;10(4):e0123068.
Species: Human
Sample Types: Cell Culture Supernates
Sputum IgE and cytokines in asthma: relationship with sputum cellular profile.
Authors: Manise M, Holtappels G, Van Crombruggen K, Schleich F, Bachert C, Louis R
PLoS ONE, 2013-03-26;8(0):U111.
Species: Human
Sample Types: Sputum
Elevated cerebral spinal fluid cytokine levels in boys with cerebral adrenoleukodystrophy correlates with MRI severity.
Authors: Lund TC, Stadem PS, Panoskaltsis-Mortari A, Raymond G, Miller WP, Tolar J, Orchard PJ
PLoS ONE, 2012-02-16;7(2):e32218.
Species: Human
Sample Types: Serum
Effect of Lactobacillus paracasei ST11 on a nasal provocation test with grass pollen in allergic rhinitis.
Authors: Wassenberg J, Nutten S, Audran R, Barbier N, Aubert V, Moulin J, Mercenier A, Spertini F
Clin. Exp. Allergy, 2011-04-01;41(4):565-73.
Species: Human
Sample Types: Nasal Fluid
Serum IL-6: a candidate biomarker for intracranial pressure elevation following isolated traumatic brain injury.
Authors: Hergenroeder GW, Moore AN, McCoy JP
J Neuroinflammation, 2010-03-11;7(0):19.
Species: Human
Sample Types: Serum
Clinical efficacy and immune regulation with peanut oral immunotherapy.
Authors: Jones SM, Pons L, Roberts JL, Scurlock AM, Perry TT, Kulis M, Shreffler WG, Steele P, Henry KA, Adair M, Francis JM, Durham S, Vickery BP, Zhong X, Burks AW
J. Allergy Clin. Immunol., 2009-07-03;124(2):292-300, 300..
Species: Human
Sample Types: Cell Culture Supernates
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.
Authors: Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP
J. Immunol., 2009-05-15;182(10):6460-9.
Species: Human
Sample Types: Cell Culture Supernates
Cigarette smoke facilitates allergen penetration across respiratory epithelium.
Authors: Gangl K, Reininger R, Bernhard D, Campana R, Pree I, Reisinger J, Kneidinger M, Kundi M, Dolznig H, Thurnher D, Valent P, Chen KW, Vrtala S, Spitzauer S, Valenta R, Niederberger V
Allergy, 2008-12-16;64(3):398-405.
Species: Human
Sample Types: Cell Culture Supernates
Critical and differential roles of NKp46- and NKp30-activating receptors expressed by uterine NK cells in early pregnancy.
Authors: El Costa H, Casemayou A, Aguerre-Girr M, Rabot M, Berrebi A, Parant O, Clouet-Delannoy M, Lombardelli L, Jabrane-Ferrat N, Rukavina D, Bensussan A, Piccinni MP, Le Bouteiller P, Tabiasco J
J. Immunol., 2008-09-01;181(0):3009-17.
Species: Human
Sample Types: Cell Culture Supernates

The IgE-reactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN-gamma.
Authors: Mittermann I, Reininger R, Zimmermann M, Gangl K, Reisinger J, Aichberger KJ, Greisenegger EK, Niederberger V, Seipelt J, Bohle B, Kopp T, Akdis CA, Spitzauer S, Valent P, Valenta R
J. Invest. Dermatol., 2007-12-13;128(6):1451-9.
Species: Human
Sample Types: Cell Culture Supernates

Inhibition of human cord blood-derived mast cell responses by anti-Fc epsilon RI mAb 15/1 versus anti-IgE Omalizumab.
Authors: Mirkina I, Schweighoffer T, Kricek F
Immunol. Lett., 2007-03-01;109(2):120-8.
Species: Human
Sample Types: Cell Culture Supernates

A neoadjuvant/adjuvant randomized trial of colorectal cancer patients vaccinated with an anti-idiotypic antibody, 105AD7, mimicking CD55.
Authors: Ullenhag GJ, Spendlove I, Watson NF, Indar AA, Dube M, Robins RA, Maxwell-Armstrong C, Scholefield JH, Durrant LG
Clin. Cancer Res., 2006-11-22;12(24):7389-96.
Species: Human
Sample Types: Cell Culture Supernates

Biological material on inhaled coarse fraction particulate matter activates airway phagocytes in vivo in healthy volunteers.
Authors: Alexis NE, Lay JC, Zeman K, Bennett WE, Peden DB, Soukup JM, Devlin RB, Becker S
J. Allergy Clin. Immunol., 2006-04-27;117(6):1396-403.
Species: Human
Sample Types: Saliva

Coengagement of CD16 and CD94 receptors mediates secretion of chemokines and induces apoptotic death of naive natural killer cells.
Authors: Jewett A, Cacalano NA, Head C, Teruel A
Clin. Cancer Res., 2006-04-01;12(7):1994-2003.
Species: Human
Sample Types: Cell Culture Supernates