Human L1TD1 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB8317R Datasheet / COA / SDS

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FAB8317R-100UG

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Human L1TD1 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human L1TD1 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG1 Clone # 901258

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human L1TD1
Met1-Leu142
Accession # Q5T7N2

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: L1TD1

L1TD1 (LINE-1 type transposase domain-containing protein 1; also known as ES cell-associated protein 11 and FLJ10884) is an RNA binding protein with a reported molecular weight of approximately 100 kDa. It is 865 amino acids (aa) in length and shares 43% aa identity with mouse L1TD1. L1TD1 is a marker for undifferentiated pluripotent stem cells. Knock down of its expression in these cells has been shown to decrease the expression of critical pluripotency factors such as Nanog and Oct-3/4. L1TD1 function in stem cells is likely regulated by its interaction with factors such as LIN-28 and is suggested to regulate RNA processing.

Long Name

LINE-1 Type Transposase Domain Containing 1

Entrez Gene IDs

54596 (Human); 381591 (Mouse); 685355 (Rat)

Alternate Names

ECAT11; ES cell-associated protein 11; FLJ10884; L1TD1; LINE-1 type transposase domain containing 1; LINE-1 type transposase domain-containing protein 1; MGC133253; RP5-1155K23.3