Human OAS2 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB1925G Datasheet / COA / SDS

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FAB1925G-100UG

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Human OAS2 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human OAS2.

Source

Monoclonal Mouse IgG2a Clone # HLS56/3

Purification

Protein A or G purified

Immunogen

2â€™,5â€™-Oligoadenylate Synthetase-2

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Immunoprecipitation

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: OAS2

OAS2, also known as OAS (69 kDa), is one of three related proteins (along with OAS1 and OAS3) that catalyze the conversion of ATP into 2’,5’-linked adenosine oligomers with the general formula pppA(2’,5’A)_n where n > 1 (2, 3) These proteins are induced by interferons, activated by double-stranded RNA, and are implicated in anti-viral immunity (1, 4, 5).

Long Name

2’,5’-Oligoadenylate Synthetase-2

Entrez Gene IDs

4939 (Human)

Alternate Names

(2-5')oligo(A) synthase 2; (2'-5')oligo(A) synthetase 2; (2-5')oligo(A) synthetase 2; 2'5' oligoadenylate synthetase 2; 2-5A synthase 2; 2-5A synthetase 2; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2 (69-71 kD); 2'-5'-oligoadenylate synthetase 2, 69/71kDa; EC 2.7.7; EC 2.7.7.-; MGC78578; OAS2; p69 OAS / p71 OAS; p69OAS / p71OAS