Human SLX4 Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB11246X Datasheet / COA / SDS

Recombinant Monoclonal Antibody

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FAB11246X-100UG

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All SLX4 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human SLX4 Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects Human SLX4 immunogen sequences in Direct ELISA.

Source

Monoclonal Rabbit IgG Clone # 2392A

Purification

Protein A or G purified

Immunogen

Synthetic peptide within amino acids 400-500 of the Human SLX4 protein sequence

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: SLX4

SLX4 (also known as BTBD12 and FANCP) is a multidomain scaffold protein involved in DNA repair, where it has important roles in the final steps of homologous recombination. SLX4 hat interacts with three distinct nucleases: SLX1, ERCC4/XPF-ERCC1 and MUS81-EME1. Mutations in the gene are associated with the disease Fanconi anemia, a rare recessive disorder characterized by genome instability, congenital malformations, progressive bone marrow failure and predisposition to hematologic malignancies and solid tumors.

Long Name

SLX4 Structure-Specific Endonuclease Subunit

Entrez Gene IDs

84464 (Human); 52864 (Mouse)

Alternate Names

BTB (POZ) domain containing 12; BTB/POZ domain-containing protein 12; BTBD12; BTBD12structure-specific endonuclease subunit SLX4; FANCP; KIAA1784; KIAA1784MUS312; KIAA1987; KIAA1987FANCP; SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); SLX4