Human TCL1A Alexa Fluor® 750-conjugated Antibody

Catalog #: AF4847S Datasheet / COA / SDS

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AF4847S-100UG

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All TCL1A Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human TCL1A Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human TCL1A in Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human TCL1A
Met1-Asp114
Accession # P56279

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TCL1A

TCL1A (T cell leukemia protein 1A; also p14 TCL1) is a 14 kDa member of the TCL1 family of proteins. It is expressed by thymocytes and activated T and B lymphocytes, and interacts with Akt kinase, promoting its activation and the subsequent deactivation of proapoptotic molecules. Human TCL1A is 114 amino acids (aa) in length. The amino acids Asp16 and Ile74 mediate Akt association, while Pro36 Leu37 Thr38 mediates TCL1A homodimerization. Full length human TCL1A is 50% aa identical to mouse TCL1A.

Long Name

T Cell Leukemia Protein 1A

Entrez Gene IDs

8115 (Human); 21432 (Mouse); 690575 (Rat)

Alternate Names

Oncogene TCL1; Oncogene TCL-1; Protein p14 TCL1; T-cell leukemia/lymphoma 1A; T-cell lymphoma-1; T-cell lymphoma-1A; TCL1A; TCL1-PEN; TCL1T-cell leukemia/lymphoma protein 1A