Human TGF-beta 1 (NP_000651) VersaClone cDNA

R&D Systems | Catalog # RDC1892

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Key Product Details

Species

Human

Accession Number

NP_000651

Background: TGF-beta 1

TGF-beta 1 (Transforming Growth Factor beta 1) is a pleiotrophic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta 1 associates with LAP to form a latent complex. It can be is activated from latency by plasmin, matrix metalloproteases, thrombospondin 1, and a subset of integrins. TGF-beta 1 signals through complexes of TGF-beta RII with TGF-beta RI/ALK-5 or ALK-1. TGF-beta signaling is modulated by the accessory receptors TGF-beta RIII/Betaglycan and Endoglin/CD105.

Long Name

Transforming Growth Factor beta 1

Alternate Names

TGF beta1, TGFB, TGFB1, TGFbeta 1

Entrez Gene IDs

7040 (Human); 21803 (Mouse); 59086 (Rat); 397078 (Porcine); 100033900 (Equine)

Gene Symbol

TGFB1

UniProt

NP_000651

Additional TGF-beta 1 Products

Product Documents for Human TGF-beta 1 (NP_000651) VersaClone cDNA

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Product Specific Notices for Human TGF-beta 1 (NP_000651) VersaClone cDNA

For research use only

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