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Recombinant Ferret IL-1 RAcP/IL-1 R3 Protein

Name: Recombinant Ferret IL-1 RAcP/IL-1 R3 Protein
Brand: Novus Biologicals
SKU: NBP3-57526
Price: 1229 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-57526

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Product Specifications
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Applications

Western Blot, ELISA, Cell Culture

View all IL-1 RAcP/IL-1 R3 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein corresponding to 151 aa of Ferret IL-1 RAcP/IL-1 R3.

Source: Yeast

Amino Acid Sequence: HPSGKRPCRM QVFRIWDINQ KTFYLRNNQL VAGYLQGSNT KLEEKLDVVP IEPHTVFLGI HGGKLCLSCV KSGDETRLQL EAVNITDLSK SKDQDKRFTF ILSDSGPTTR FESAACPGWF LCTALEADRP VSFTNTPEEA RTVTKFYFQK D (151)

Stable for up to 12 months from date of receipt at -20C. Stable for 3 months when stored in working aliquots with a carrier protein at -20C. Avoid repeated freeze/thaw cycles.

Purity

>98%, by SDS-PAGE

Endotoxin Level

No affinity tags & naturally endotoxin-free

Predicted Molecular Mass

17.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Enzyme-linked Immunosorbent Spot (ELISPOT)
ELISA Standard (Matched Pair) (ELISA(Sta))

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation, and Storage

NBP3-57526

Formulation	Lyophilized in 1-5X PBS containing 10% Trehalose
Preservative	10% Trehalose
Concentration	Lyoph
Reconstitution	Reconstitute in sterile PBS with at least 0.1% carrier protein
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: IL-1 RAcP/IL-1 R3

Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently (1,2). IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response (3). IRAK mediates a signaling cascade leading to NF-kappaB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF) (1,4).

Long Name

Interleukin 1 Receptor Accessory Protein

Alternate Names

IL-1 R3, IL-1RAcP, IL1RAcP, IL1RAP

Gene Symbol

IL1RAP

Additional IL-1 RAcP/IL-1 R3 Products

Product Documents for Recombinant Ferret IL-1 RAcP/IL-1 R3 Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Ferret IL-1 RAcP/IL-1 R3 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.