Recombinant Canine IL-24 Protein

Novus Biologicals | Catalog # NBP3-57421

Novus Biologicals
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Key Product Details

Applications

Western Blot, ELISA, Cell Culture
View all IL-24 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein corresponding to 155 aa of Canine IL-24.

Source: Yeast

Amino Acid Sequence: QEFRFGPCRV QGVALRELRE AFWTVKDTVQ AKDNITSVRL LRKEVLQDVS DAESCYLIRA LLKFYLNTVF KNYLDEAADV RIRRSFSTLA NNFFVIASKL QPSQEDEMFS ISESARRRFL LFQRAFKQLD IQAAQTKAFG EVDILLTWME KFYEF (155)

Stable for up to 12 months from date of receipt at -20C. Stable for 3 months when stored in working aliquots with a carrier protein at -20C. Avoid repeated freeze/thaw cycles.

Purity

>98%, by SDS-PAGE

Endotoxin Level

No affinity tags & naturally endotoxin-free

Predicted Molecular Mass

18.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Enzyme-linked Immunosorbent Spot (ELISPOT)
ELISA Standard (Matched Pair) (ELISA(Sta))

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation, and Storage

NBP3-57421
Formulation Lyophilized in 1-5X PBS containing 10% Trehalose
Preservative 10% Trehalose
Reconstitution Reconstitute in sterile PBS with at least 0.1% carrier protein
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-24

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Long Name

Interleukin 24

Alternate Names

C49A, FISP, IL24, MDA-7, MOB-5, ST16

Gene Symbol

IL24

Additional IL-24 Products

Product Documents for Recombinant Canine IL-24 Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Canine IL-24 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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