Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunocytochemistry

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 308202
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Product Specifications

Immunogen

E. coli-derived recombinant human IL-31
Ser24-Thr164
Accession # Q6EBC2

Specificity

Detects human IL‑31 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse IL‑31 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for IL-31 Antibody (308202) [DyLight 488]

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-31

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting ofIL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma(Dillon et al., 2004 (PubMed 15184896)).(supplied by OMIM)

Long Name

Interleukin 31

Alternate Names

IL31

Gene Symbol

IL31

Additional IL-31 Products

Product Documents for IL-31 Antibody (308202) [DyLight 488]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IL-31 Antibody (308202) [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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Associated Pathways

Th2 Differentiation Pathway Th2 Differentiation Pathway Thumbnail