M-CSF Antibody Pair [Biotin]

Novus Biologicals | Catalog # NBP3-57745

Novus Biologicals
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Key Product Details

Assay Type

Sandwich ELISA

Sample Type

Cell culture supernatants from cats (Felis catus). Can also be used in additional biological sample types reported in the literature reported in the literature, including serum, plasma, peripheral blood mononuclear cell (PBMC) culture supernatants, bone marrow-derived cell cultures, and tissue lysates, with minor protocol modifications recommended to optimize assay performance across different matrices. (100 ul)

Reactivity

Feline
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Product Specifications

Description

The ELISA kit contains a capture antibody, detection antibody, and recombinant protein standard validated to function together in an optimized ELISA format; kit components are not supplied in matched quantities and may be purchased separately. This product is for research use only.

Sample Volume Required

100 ul

Conjugate

Biotin

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Storage of components varies. See protocol for specific instructions.

Background: M-CSF

M-CSF (macrophage colony stimulating factor, colony stimulating factor 1, CSF-1) is a hemtopoietic growth factor produced by monocytes, granulocytes, endothelial cells, fibroblasts and activated B-cells and T-cells. M-CSF stimulates macrophage colony formation and regulates proliferation and differentiation of hematopoeitic stem cells into macrophages and regulates survival and differentiation of monocytes. It enhances antibody-dependent cell-mediated cytotoxity, enhances marophage killing of tumor cells and microorganisms, regulates the release of cytokines and inhibits bone resorption by osteoclasts. Human M-CSF shows biological activity on murine and rat cells and although murine M-CSF is active in rat cells it is inactive in human cells.

Long Name

Macrophage Colony Stimulating Factor

Alternate Names

CSF-1, CSF1, Lanimostim, MCSF

Gene Symbol

CSF1

Additional M-CSF Products

Product Documents for M-CSF Antibody Pair [Biotin]

Certificate of Analysis

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Product Specific Notices for M-CSF Antibody Pair [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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