Mouse Reg1 Alexa Fluor® 488-conjugated Antibody

Catalog #: AF1657G Datasheet / COA / SDS

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AF1657G-100UG

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Mouse Reg1 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Reg1 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse (rm) Reg2 is observed and less than 5% cross-reactivity with rmReg3A, recombinant human (rh) Reg1B, rhRe

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse Reg1
Gln22-Gly165
Accession # P43137

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Reg1

Reg1, also known as pancreatic thread protein (PTP), pancreatic stone protein (PSP) and lithostathine, is the founding member of the Reg family of proteins, which are secreted proteins with a C-type lectin domain. Reg1 is expressed during islet regeneration. Reg1 functions in an autocrine/paracrine fashion via a cell surface Reg receptor that mediates a growth signal for beta -cell regeneration (1).

Long Name

Regenerating Islet-derived 1

Entrez Gene IDs

19692 (Mouse)

Alternate Names

ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; lithostathine-1-alpha; Pancreatic stone protein; pancreatic stone protein, secretory; Pancreatic thread protein; protein-X; PSPregenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic threadprotein); PSPS1REG-1-alpha; PSPSMGC12447; PTPP19; Reg1; regenerating islet-derived 1 alpha; Regenerating islet-derived protein 1-alpha; Regenerating protein I alpha; REGlithostathine 1 alpha