Mouse Reg1 Antibody [Biotin]

R&D Systems | Catalog # BAF1657

R&D Systems

Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Sheep IgG
View all Reg1 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse Reg1
Gln22-Gly165
Accession # P43137

Specificity

Detects mouse Reg1 in Western blots. In this format, approximately 10% cross-reactivity with recombinant mouse (rm) Reg2 is observed and less than 5% cross-reactivity with rmReg3A, recombinant human (rh) Reg1B, rhReg4 and recombinant rat Reg3 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Mouse Reg1 Antibody [Biotin]

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse Reg1

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Reg1

Reg1, also known as pancreatic thread protein (PTP), pancreatic stone protein (PSP) and lithostathine, is the founding member of the Reg family of proteins, which are secreted proteins with a C-type lectin domain. Reg1 is expressed during islet regeneration. Reg1 functions in an autocrine/paracrine fashion via a cell surface Reg receptor that mediates a growth signal for beta -cell regeneration (1).

References

  1. Okamoto, H. and S. Takasawa (2002) Diabetes 51:5462.

Long Name

Regenerating Islet-derived 1

Alternate Names

ICRF, Islet cells regeneration factor, Islet of Langerhans regenerating protein, lithostathine-1-alpha, Pancreatic stone protein, pancreatic stone protein, secretory, Pancreatic thread protein, protein-X, PSPregenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic threadprotein), PSPS1REG-1-alpha, PSPSMGC12447, PTPP19, regenerating islet-derived 1 alpha, Regenerating islet-derived protein 1-alpha, Regenerating protein I alpha, REGlithostathine 1 alpha

Entrez Gene IDs

19692 (Mouse)

Gene Symbol

REG1

UniProt

P43137

Additional Reg1 Products

Product Documents for Mouse Reg1 Antibody [Biotin]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse Reg1 Antibody [Biotin]

For research use only

Related Research Areas

C-type Lectin Family
Diabetes

Citations for Mouse Reg1 Antibody [Biotin]

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