Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunocytochemistry

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2A Clone # 787924
View all PDZD2 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human PDZD2
Ser2489-Ser2839
Accession # O15018

Specificity

Detects human PDZD2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse PDZD2 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Applications for PDZD2/PDZK3 Antibody (787924) [Biotin]

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PDZD2

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. Two transcript variants encoding different isoforms have been found for this gene.

Long Name

PDZ Domain Containing 2

Alternate Names

AIPC, KIAA0300, Papin, Pin1

Gene Symbol

PDZD2

Additional PDZD2 Products

Product Documents for PDZD2/PDZK3 Antibody (787924) [Biotin]

Certificate of Analysis

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Product Specific Notices for PDZD2/PDZK3 Antibody (787924) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers
p53 Pathway

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Protocols

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FAQs

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