Best Seller

Simple Plex Control for Human CXCL10/IP-10/CRG-2

Name: Simple Plex Control for Human CXCL10/IP-10/CRG-2
Brand: R&D Systems
SKU: 894949
Price: 150 USD
Availability: InStock

R&D Systems | Catalog # 894949

Submit a review

Citations

Product Documents

Control for use with Human and Non-Human Primate CXCL10/IP-10/CRG-2 Simple Plex Cartridge Kit

Product Summary
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human, Non-human Primate

Applications

Control, Simple Plex Automated Immunoassay

Product Summary for Simple Plex Control for Human CXCL10/IP-10/CRG-2

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human and NHP CXCL10/IP-10/CRG-2 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Background: CXCL10/IP-10/CRG-2

CXCL10/IP-10 is an ELR- angiostatic chemokine that interacts with CXCR3 to attract Th1 cells, eosinophils, monocytes, and NK cells to sites of inflammation. It is upregulated by activated T lymphocytes, neutrophils, splenocytes, keratinocytes, osteoblasts, astrocytes, endothelial cells, smooth muscle cells, and pancreatic beta cells. CXCL10 contributes to disease pathology in many chronic inflammatory disorders including rheumatoid arthritis, psoriasis, cancer, multiple sclerosis, diabetes, and cardiovascular disease.