6 results for "3C and 3CL Protease Inhibitors" in 产品

3C and 3CL Protease Inhibitors

3C and 3C-like proteases are cysteine proteases identified in coronaviruses and picornaviruses, such as SARS-CoV, poliovirus and rhinovirus. The active form of these proteases is dimeric, with each monomer contributing a cysteine-histidine catalytic domain to the active site. The individual monomers are inactive without dimerization. 3C and 3CL proteases are essential to the life cycle of the virus, and are key to the proteolytic processing of polyproteins that are translated from viral RNA by ...

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Proteasome and calpain inhibitor. Inhibits NF-κB activation

Alternate Names: Z-LLL-al,Z-Leu-Leu-Leu-CHO
Chemical Name: N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide
Purity: ≥95%
Proteasome and calpain inhibitor. Inhibits NF-κB activation
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Non-selective PI 3-kinase inhibitor

Chemical Name: 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
Purity: ≥98%
Non-selective PI 3-kinase inhibitor
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Coronavirus Mpro inhibitor

Chemical Name: tert-Butyl (1-((S)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate
Purity: ≥97%
Coronavirus Mpro inhibitor
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Coronavirus Mpro inhibitor

Chemical Name: N-[(5-Methyl-3-isoxazolyl)carbonyl]-L-alanyl-L-valyl-N-[(1S,2E)-4-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]-4-(phenylmethoxy)-2-buten-1-yl]-L-leucinamide
Purity: ≥98%
Coronavirus Mpro inhibitor
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Potent non-covalent inhibitor of SARS-CoV-2 main protease

Chemical Name: 5-[5-[3-Chloro-5-[(2-chlorophenyl)methoxy]-4-fluorophenyl]-6-oxo[1(6H),3'-bipyridin]-3-yl]-1-methyl-2,4(1H,3H)-pyrimidinedione
Purity: ≥95%
Potent non-covalent inhibitor of SARS-CoV-2 main protease
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Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

Chemical Name: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
Purity: ≥98%
Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor
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