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168 results for "Calcium-sensing R/CaSR" in 产品

Calcium-sensing R/CaSR Products

Calcium-Sensing Receptor (CaSR) is a member of the G protein-coupled receptor family. CaSR is an integral membrane protein that senses changes in the extracellular concentration of calcium ions and controls the release of parathyroid hormone. The activity of the calcium-sensing receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.

Mutations that inactivate CaSR lead to familial hypocalciuric hypercalcemia, whereas mutations that activate CaSR cause autosomal dominant hypocalcemia. Calcium-Sensing Receptor antibodies are useful tools for parathyroid studies and research on cellular calcium homeostasis regulation.

Negative allosteric modulator of calcium-sensing receptor (CaSR)

Chemical Name: 4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-benzamide hydrochloride
Purity: ≥98%
Negative allosteric modulator of calcium-sensing receptor (CaSR)
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Reactivity: Human, Mouse, Rat, Porcine, Bovine
Details: Mouse IgG2A Monoclonal Clone #5C10, ADD
Applications: IHC, WB, ELISA, ICC/IF
Western Blot: Calcium-sensing R/CaSR Antibody (5C10, ADD)BSA Free [NB120-19347]
(7)
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Reactivity: Human, Mouse, Rat, Rabbit
Details: Mouse IgG1 kappa Monoclonal Clone #HL 1499
Applications: WB, ELISA, Flow, Simple Western, IP, + 1 More
Western Blot: Calcium-sensing R/CaSR Antibody (HL 1499)BSA Free [NB100-1830]
(8)
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Reactivity: Human, Mouse, Rat, Rabbit
Details: Mouse IgG1 kappa Monoclonal Clone #HL 1499
Applications: IHC, WB, ELISA, Flow, ICC/IF, + 3 More
Western Blot: Calcium-sensing R/CaSR Antibody (HL 1499)Azide and BSA Free [NBP2-80607]
(8)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB
Immunohistochemistry-Paraffin: Calcium-sensing R/CaSR Antibody [NBP2-38622]
(8)
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB
Western Blot: Calcium-sensing R/CaSR Antibody [NBP1-84687]
(15)
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Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat, Feline
Details: Rabbit IgG Monoclonal Clone #HL2357
Applications: IHC, WB
Calcium-sensing R/CaSR Antibody (HL2357) - Azide and BSA Free
(7)
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Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ELISA, ICC/IF
Calcium-sensing R/CaSR Antibody - BSA Free
(3)
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Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #611825
Applications: Flow, CyTOF-ready
Detection of Calcium-sensing R/CaSR antibody in HEK293 Human Cell Line Transfected with Human Calcium-sensing R/CaSR and eGFP antibody by Flow Cytometry.
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Positive allosteric modulator of human calcium-sensing receptor (CaSR)

Chemical Name: 2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine hydrochloride
Purity: ≥98%
Positive allosteric modulator of human calcium-sensing receptor (CaSR)
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Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #PSH03-47
Applications: IHC, WB
Calcium-sensing R/CaSR Antibody (PSH03-47)
(2)
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Selective calcium-sensing receptor (CaSR) antagonist; orally active calcilytic agent

Chemical Name: 2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino-2-hydroxypropoxy]benzonitrile hydrochloride
Purity: ≥98%
Selective calcium-sensing receptor (CaSR) antagonist; orally active calcilytic agent
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Reactivity: Human
Source: HEK293
Accession #: P41180-1
R&D Systems Recombinant Proteins and Enzymes
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Reactivity: Human
R&D Systems VersaClone cDNA Plasmids
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Biased allosteric modulator of calcium-sensing receptor (CaSR)

Chemical Name: α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol
Purity: ≥98%
Biased allosteric modulator of calcium-sensing receptor (CaSR)
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Allosteric Calcium-sensing receptor (CaSR) agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailable

Alternate Names: AMG 073
Chemical Name: N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride
Purity: ≥98%
Allosteric Calcium-sensing receptor (CaSR) agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailable
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Reactivity: Human
Applications: WB
Western Blot: Calcium-sensing R/CaSR Overexpression Lysate [NBL1-08721]
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Reactivity: Human
Sensitivity: 0.47 ng/mL
Assay Range: 0.78 - 50 ng/mL
Applications: ELISA
Human Calcium-sensing R/CaSR ELISA Kit (Colorimetric)
(2)
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Reactivity: Mouse
Sensitivity: 0.10 ng/mL
Assay Range: 0.16 - 10 ng/mL
Applications: ELISA
Mouse Calcium-sensing R/CaSR ELISA Kit (Colorimetric)
(2)
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Reactivity: Rat
Sensitivity: 0.10 ng/mL
Assay Range: 0.16 - 10 ng/mL
Applications: ELISA
Rat Calcium-sensing R/CaSR ELISA Kit (Colorimetric)
(2)
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Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #611825
Applications: Flow, CyTOF-ready
Human Calcium-sensing R/CaSR Antibody (611825) [Alexa Fluor™ Plus 405]
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Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #611825
Applications: Flow, CyTOF-ready
Human Calcium-sensing R/CaSR Antibody (611825) [Alexa Fluor™ Plus 488]
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Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #611825
Applications: Flow, CyTOF-ready
Human Calcium-sensing R/CaSR Antibody (611825) [Alexa Fluor™ Plus 555]
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Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #611825
Applications: Flow, CyTOF-ready
Human Calcium-sensing R/CaSR Antibody (611825) [Alexa Fluor™ Plus 594]
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Reactivity: Human
Details: Mouse IgG2A Monoclonal Clone #611825
Applications: Flow, CyTOF-ready
Human Calcium-sensing R/CaSR Antibody (611825) [Alexa Fluor™ Plus 647]
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