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2 results for "Calpain Inhibitors" in 产品
Calpain Inhibitors
Calpains are a group of calcium-sensitive cysteine proteases that are ubiquitously expressed in mammals. This family contains 14 members, with μ-calpain (calpain 1) and m-calpain (calpain 2) being the most well-characterized. Structurally, calpains contain two subunits; an 80 kDa catalytic subunit and a 28 kDa regulatory subunit that functions as a chaperone to stabilize the 80 kDa structure.
Calpains are regulated by Ca2+ concentration, phosphorylation, calpastatin and probably by altering ...
Proteasome and calpain inhibitor. Inhibits NF-κB activation
| Alternate Names: | Z-LLL-al,Z-Leu-Leu-Leu-CHO |
| Chemical Name: | N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide |
| Purity: | ≥95% |
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Potent ATG4B/autophagin-1 inhibitor; also inhibits calpain and cathepsin B
| Chemical Name: | N-[(1S)-2-[(3-Fluoro-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-1-naphthalenecarboxamide |
| Purity: | ≥90% |
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