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1 result for "CDK1 Subfamily Degraders Small Molecules and Peptides" in 产品
CDK1 Subfamily Degraders Small Molecules and Peptides
The CDK1 subfamily of cyclin-dependent kinases includes CDK1, CDK2 and CDK3. All three members of this family can bind cyclin A, cyclin B, cyclin E and possibly cyclin C, and are fundamentally involved in regulation of the cell cycle.
CDK1
CDK1 is a 34kDa protein that is highly conserved and is essential for cell cycle progression in mammals. The roles of CDK2 and CDK3 in the cell cycle are dispensable as CDK1 can interact with multiple different cyclins to compensate if CDK2 and/or CDK3 are ...
Potent and selective CDK2 Degrader (PROTAC®)
| Chemical Name: | 4-[[5-Amino-1-[(3-methyl-2-thienyl)carbonyl]-1H-1,2,4-triazol-3-yl]amino]-N-[2-[[1-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]ethyl]benzenesulfonamide |
| Purity: | ≥98% |
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