199 results for "CDK2" in 产品
CDK2 Products
CDK2 (cyclin-dependent kinase 2), a serine/threonine protein kinase, is the catalytic subunit of the heterodimeric cyclin-dependent kinase complex required for G1/S phase transition. The kinase activity of CDK2 is regulated by the association with a cyclin subunit, CDK inhibitors, and its phosphorylation state. The active CDK2/cyclin A complex interacts with the N-terminus of E2F-1 and directs the phosphorylation of E2F-1 and DP-1. The active CDK2/cyclin E complex phosphorylates Rb which ...
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Simple Western |
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Mouse IgG2A Monoclonal Clone #OTI2D9 |
| Applications: | IHC, WB, Flow, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #1A6 |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF, + 1 More |
![Western Blot: CDK2 Antibody (1A6)BSA Free [NBP2-37507]](https://resources.rndsystems.com/images/products/CDK2-Antibody-1A6-Western-Blot-NBP2-37507-img0003.jpg "Western Blot: CDK2 Antibody (1A6)BSA Free [NBP2-37507]")
| Reactivity: | Human, Mouse, Rat, Canine, Monkey |
| Details: | Mouse IgG2A Monoclonal Clone #OTI2D9 |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
![Western Blot: CDK2 Antibody (OTI2D9)Azide and BSA Free [NBP2-70392]](https://resources.rndsystems.com/images/products/CDK2-Antibody-OTI2D9-Azide-and-BSA-Free-Western-Blot-NBP2-70392-img0002.jpg "Western Blot: CDK2 Antibody (OTI2D9)Azide and BSA Free [NBP2-70392]")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL7990 |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: CDK2 Antibody (CL7990) [NBP2-88911]](https://resources.rndsystems.com/images/products/CDK2-Antibody-CL7990-Immunohistochemistry-Paraffin-NBP2-88911-img0006.jpg "Immunohistochemistry-Paraffin: CDK2 Antibody (CL7990) [NBP2-88911]")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL7990 |
| Applications: | IHC, WB, ICC/IF |
![CDK2 Antibody (CL7990) - Azide and BSA Free Immunohistochemistry-Paraffin: CDK2 Antibody [NBP3-44198]](https://resources.rndsystems.com/images/products/nbp3-44198_mouse-cdk2-mab-cl7990-azide-and-bsa-free-28220251211539.jpg "Immunohistochemistry-Paraffin: CDK2 Antibody [NBP3-44198]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SN72-04 |
| Applications: | IHC, WB, IP |
HMG-CoA reductase inhibitor
| Chemical Name: | (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethyl butanoate |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Xenopus |
| Details: | Mouse IgG2A Monoclonal Clone #AN4.3 |
| Applications: | WB, ELISA, Flow, IP, CyTOF-ready |
Potent HMG-CoA reductase inhibitor
| Alternate Names: | Mevinolin |
| Chemical Name: | (2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl-2-methyl butanoate |
| Purity: | ≥97% |
Cdk inhibitor
| Alternate Names: | CYC 202,Seliciclib |
| Chemical Name: | (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: CDK2 [p Thr160] Antibody [NBP3-13301]](https://resources.rndsystems.com/images/products/CDK2-[p-Thr160]-Antibody-Western-Blot-NBP3-13301-img0004.jpg "Western Blot: CDK2 [p Thr160] Antibody [NBP3-13301]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Immunohistochemistry-Paraffin: CDK2 [p Thr160] Antibody - Azide and BSA Free [NBP3-05409]](https://resources.rndsystems.com/images/products/CDK2-[p-Thr160]-Antibody-Immunohistochemistry-Paraffin-NBP3-05409-img0001.jpg "Immunohistochemistry-Paraffin: CDK2 [p Thr160] Antibody - Azide and BSA Free [NBP3-05409]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1560 |
| Applications: | IHC, WB, IP |
GSK-3β inhibitor; also inhibits cdks
| Chemical Name: | 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one |
| Purity: | ≥98% |
Cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5
| Alternate Names: | NG 60 |
| Chemical Name: | (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol |
| Purity: | ≥98% |
Selective cdk inhibitor; potently inhibits cdk1, cdk2 and cdk5
| Alternate Names: | NG 95 |
| Chemical Name: | (2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol |
| Purity: | ≥98% |
Cdk inhibitor; potently inhibits cdk2 and cdk9
| Alternate Names: | L 86-8275 |
| Chemical Name: | 2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one hydrochloride |
| Purity: | ≥98% |
Cdk2 inhibitor; also potent inhibitor of aurora kinase A and B
| Chemical Name: | 4-[[6-(Cyclohexylmethoxy)-1H-purin-2-yl]amino]-N,N-diethylbenzamide |
| Purity: | ≥98% |
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9
| Chemical Name: | 4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
| Purity: | ≥98% |
Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9
| Alternate Names: | BMS-387032 |
| Chemical Name: | N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide |
| Purity: | ≥98% |
Potent and selective DYRK1A inhibitor
| Chemical Name: | 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole |
| Purity: | ≥98% |
Potent cdk inhibitor
| Chemical Name: | 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol |
| Purity: | ≥98% |
Potent and selective cdk inhibitor; orally bioavailable
| Chemical Name: | [4-Amino-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-5-pyrimidinyl](2,3-difluoro-6-methoxyphenyl)methanone |
| Purity: | ≥98% |
Cdk inhibitor; potently inhibits cdk1 and cdk2
| Chemical Name: | (4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl) (2,6-difluoro-4-methylphenyl)methanone |
| Purity: | ≥97% |
