11 results for "CRISPR Reagents Small Molecules and Peptides" in 产品
CRISPR Reagents Small Molecules and Peptides
CRISPR (clustered regularly interspaced short palindromic repeats) is a technology for the targeted editing and regulation of genes that can be applied to a number of biological systems. Tocris offers small molecules that can enhance the efficiency of the CRISPR-mediated gene editing process.
CRISPR are sections of prokaryotic DNA that mediate an acquired immune response against invading plasmids and viruses. The CRISPR locus is composed of Cas (CRISPR associated) genes, a leader sequence and ...
Metabolite of tamoxifen (Cat. No. 0999)
| Alternate Names: | 4-OH-TAM |
| Chemical Name: | 4-[(1Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol |
| Purity: | ≥98% |
Potent and selective DNA-PK inhibitor
| Alternate Names: | KU 57788 |
| Chemical Name: | 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one |
| Purity: | ≥98% |
Viral transduction enhancer
| Alternate Names: | Hexadimethrine bromide |
| Chemical Name: | 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide |
| Purity: | ≥95% |
Microtubule inhibitor
| Chemical Name: | [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbamic acid methyl ester |
| Purity: | ≥95% |
Disrupts protein translocation to Golgi
| Chemical Name: | 1,6,7,8,9,11aβ,12,13,14,14aα-Decahydro-1β,13α-dihydroxy-6β-methyl-4H-cyclopent[f]oxacyclotridecin-4-one |
| Purity: | ≥98% |
Cdk1 inhibitor
| Chemical Name: | 5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone |
| Purity: | ≥98% |
Potent and selective Cdc7 inhibitor
| Alternate Names: | BMS 863233 |
| Chemical Name: | 8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride |
| Purity: | ≥98% |
Potent DNA-PK inhibitor; also increases CRISPR-Cas9 deletion efficiency
| Chemical Name: | 8-(4-Dibenzothienyll)-2-(4-morpholinyl)-4H-1,3-benzoxazin-4-one |
| Purity: | ≥98% |
Cell permeable and reversible Cas9 inhibitor
| Chemical Name: | (3aR,4R,9bR)-8-(2-Fluorophenyl)-2,3,3a,4,5,9b-hexahydro-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[3,2-c]quinoline-4-methanol |
| Purity: | ≥98% |
Potent hepatitis C virus (HCV) NS3 protease inihibitor
| Chemical Name: | 1-[[N-tert-Butoxycarbonyl-L-tert-leucyl-trans-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-L-prolyl]amino]-N-(cyclopropylsulfonyl)-(1R,2S)-2-vinylcyclopropane-1-carboxamide |
| Purity: | ≥98% |
preQ1 with alkyne handle for click chemistry
| Chemical Name: | N-[6-[[(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]amino]hexyl]-3-(2-propyn-1-yloxy)propanamide |
| Purity: | ≥95% |
