9 results for "GABA-A R epsilon Small Molecules and Peptides" in 产品
GABA-A R epsilon Small Molecules and Peptides
The product of the GABA Receptor Epsilon gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyricacid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptictransmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in acluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively splicedtranscript variants have been identified, but only one is thought to encode a protein. (provided by RefSeq)
Competitive and selective GABAA antagonist
| Alternate Names: | Gabazine |
| Chemical Name: | 6-Imino-3-(4-methoxyphenyl)-1(6H)-pyridazinebutanoic acid hydrobromide |
| Purity: | ≥98% |
GABAA agonist
| Alternate Names: | Gaboxadol |
| Chemical Name: | 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol hydrochloride |
| Purity: | ≥98% |
Benzodiazepine inverse agonist
| Chemical Name: | N-Methyl-β-carboline-3-carboxamide |
| Purity: | ≥99% |
Benzodiazepine antagonist
| Alternate Names: | Ro 15-1788 |
| Chemical Name: | 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester |
| Purity: | ≥99% |
GABAA partial agonist; displays subtype selectivity
| Chemical Name: | 3-(2,5-Difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine |
| Purity: | ≥98% |
Postitive allosteric modulator of GABAA receptors
| Chemical Name: | (3α,5β)-3-Hydroxy-pregnan-20-one |
Positive allosteric modulator of GABAA receptors
| Alternate Names: | 3a,5a-THPROG |
| Chemical Name: | (3α,5α)-3-Hydroxy-pregnan-20-one |
α5-selective GABAA inverse agonist
| Chemical Name: | 3-(1,1-Dimethylethyl)-7-(5-methyl-3-isoxazolyl)-2-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-pyrazolo[1,5-d][1,2,4]triazine |
| Purity: | ≥98% |
Active metabolite of oxcarbazepine (Cat. No. 3864)
| Alternate Names: | GP 47779 |
| Chemical Name: | 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide |
| Purity: | ≥98% |
