GLP-2 Receptor Peptides

Glucagon-like peptide 2 (GLP-2) receptors are members of the glucagon receptor family that also includes glucagon, GLP-1, secretin, GHRH and GIP receptors. GLP-2 receptors are found in the central nervous system and the gastrointestinal system, with the highest expression levels in the jejunum.

The principle role of GLP-2 receptors appears to be the maintenance of the growth and absorptive function of the intestinal mucosal villus epithelium and they have also been implicated in nutrient absorption. The human GLP-2 receptor gene is localized on chromosome 17p13.3.