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1 result for "GSK-3 Degraders" in 产品
GSK-3 Degraders
The serine/threonine kinase Glycogen synthase kinase 3 (GSK-3) has two isoforms (α and β). GSK-3 is a key enzyme in glycogen metabolism, as well as cell division, proliferation, motility and survival. The enzyme plays a role in a number of pathological conditions, including cancer, diabetes and neurological diseases.
GSK-3 phosphorylates tau and presenilin-1, which are involved in the development of Alzheimer's disease. Both isoforms of GSK-3 are ubiquitously expressed, although ...
| Chemical Name: | 3-Amino-6-(4-((4-(4-(1-(17-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaheptadecyl)-1H-1,2,3-triazol-4-yl)butyl)piperazin-1-yl)sulfonyl)phenyl)-N-(pyridin-3-yl)pyrazine-2-carboxamide |
| Purity: | ≥98% |
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