153 results for "Histone Deacetylase 4/HDAC4" in 产品
Histone Deacetylase 4/HDAC4 Products
Chromatin is a highly specialized structure composed of tightly compacted chromosomal DNA. Gene expression within the nucleus is controlled, in part, by a host of protein complexes which continuously pack and unpack the chromosomal DNA. One of the known mechanisms of this packing and unpacking process involves the acetylation and deacetylation of the histone proteins comprising the nucleosomal core. Acetylated histone proteins confer accessibility of the DNA template to the transcriptional ...
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Simple Western |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, Mycoplasma |
Histone deacetylase inhibitor
| Alternate Names: | VPA,Sodium Valproate |
| Chemical Name: | Sodium 2-propylpentanoate |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP, ChIP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, ICC/IF |
Potent histone deacetylase inhibitor
| Chemical Name: | (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide |
| Purity: | ≥95% |
Class I and II HDAC inhibitor
| Alternate Names: | Vorinostat |
| Chemical Name: | N-Hydroxy-N'-phenyloctanediamide |
| Purity: | ≥98% |
Histone deacetylase inhibitor
| Alternate Names: | 4-PB,Sodium phenylbutyrate |
| Chemical Name: | 4-Phenylbutyric acid, sodium salt |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #5E4A5 |
| Applications: | IHC, WB, ELISA, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #7E2E6 |
| Applications: | WB, ELISA, Flow, ICC/IF, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #713802 |
| Applications: | IHC |
High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic
| Chemical Name: | 1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-3-quinolinecarboxamide |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
Potent and selective class I histone deacetylase inhibitor; antitumor
| Alternate Names: | Depsipeptide,FR 901228,Romidepsin |
| Chemical Name: | Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3-5) disulfide |
| Purity: | ≥98% |
Potent and selective class IIa HDAC inhibitor; brain penetrant
| Chemical Name: | 2-(2-Fluorophenyl)-N-hydroxy-2-(4-(5-(trifluoromethyl)pyrimidin-2-yl)phenyl)acetamide |
| Purity: | ≥98% |
Pan-histone deacetylase inhibitor
| Chemical Name: | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | WB, ELISA, AP, MA |
| Reactivity: | Human |
| Applications: | AC |
| Reactivity: | Human |
Potent and selective HDAC class IIa inhibitor
| Chemical Name: | N-((R)-1-((S)-2-Methylpyrrolidin-1-yl)propan-2-yl)-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide |
| Purity: | ≥98% |
Potent and selective HDAC4 Degrader (PROTAC®)
| Chemical Name: | (2S,4R)-1-((3R,26S)-26-(tert-Butyl)-3-methyl-1,24-dioxo-5-propyl-1-(4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl)-10,13,16,19,22-pentaoxa-2,5,25-triazaheptacosan-27-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% |
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, ICC/IF |