537 results for "IGF-I R/IGF1R" in 产品
IGF-I R/IGF1R Products
IGF-I R/IGF1R (Insulin-like Growth Factor I Receptor), also known as CD221, is a ubiquitously expressed heterotetrameric transmembrane glycoprotein consisting of two alpha and two beta subunits. It binds IGF-1 with high affinity, IGF2 with lower affinity, and Insulin with lowest affinity. IGF1R/Insulin R hybrids respond primarily to IGF-1 and may downregulate cellular responses to Insulin. IGF signaling is also modulated by IGF binding proteins and the scavenger receptor, IGF-II ...
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #33255 |
| Applications: | IHC, WB, ELISA(Cap), B/N, Flow, + 1 More |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, B/N, ICC/IF |
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
| Reactivity: | Human |
| Applications: |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #3G5C1 |
| Applications: | IHC, WB, ELISA |
![Western Blot: IGF-I R/IGF1R Antibody (3G5C1)BSA Free [NB110-87052]](https://resources.rndsystems.com/images/products/IGF-I-R-Antibody-3G5C1-Western-Blot-NB110-87052-img0021.jpg "Western Blot: IGF-I R/IGF1R Antibody (3G5C1)BSA Free [NB110-87052]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Flow, ICC/IF, CyTOF-ready |
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P08069 |
| Applications: | Binding Activity |
| Reactivity: | Human, Mouse, Rat, Equine, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: IGF-I R/IGF1R AntibodyBSA Free [NBP1-77680]](https://resources.rndsystems.com/images/products/IGF-I-R-Antibody-Western-Blot-NBP1-77680-img0009.jpg "Western Blot: IGF-I R/IGF1R AntibodyBSA Free [NBP1-77680]")
Analyzed by SEC-MALS
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P08069 |
| Applications: | Binding Activity |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Simple Western |
![Western Blot: IGF-I R/IGF1R AntibodyBSA Free [NBP1-77679]](https://resources.rndsystems.com/images/products/IGF-I-R-Antibody-Western-Blot-NBP1-77679-img0009.jpg "Western Blot: IGF-I R/IGF1R AntibodyBSA Free [NBP1-77679]")
| Reactivity: | Human |
| Applications: | ELISA |
| Reactivity: | Human |
| Assay Range: | 250-16000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Source: | CHO |
| Accession #: | Q60751 |
| Applications: | Bioactivity |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #HL1957 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Assay Range: | 156-10000 pg/mL |
| Applications: | ELISA |
Selective IGF1R inhibitor
| Alternate Names: | Picropodophyllin |
| Chemical Name: | (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one |
| Purity: | ≥97% |
| Reactivity: | Human |
| Details: | Mouse IgG2c Kappa Monoclonal Clone #IGF1R/4667 |
| Applications: | IHC, Flow, ICC/IF, Func, MA |
![Immunohistochemistry-Paraffin: IGF-I R/IGF1R Antibody (IGF1R/4667) [NBP3-13948]](https://resources.rndsystems.com/images/products/IGF-I-R-IGF1R-Antibody-IGF1R-4667-Immunohistochemistry-Paraffin-NBP3-13948-img0003.jpg "Immunohistochemistry-Paraffin: IGF-I R/IGF1R Antibody (IGF1R/4667) [NBP3-13948]")
High affinity insulin-like growth factor-I binding protein IGFBP inhibitor
| Chemical Name: | 1-(3,4-Dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #33255 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![IGF-I R/IGF1R [p Tyr1165, p Tyr1166] Antibody](https://resources.rndsystems.com/images/products/nb100-81983_rabbit-polyclonal-igf-i-r-igf1r-p-tyr1165-p-tyr1166-antibody-234202415232516.jpg "Western Blot: IGF-I R/IGF1R [p Tyr1165, p Tyr1166] Antibody [NB100-81983] -")
| Reactivity: | Human |
| Source: | HEK293 |
| Applications: | Bioactivity |
Recombinant Monoclonal Antibody For Research Use Only
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu14F2 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2c Kappa Monoclonal Clone #IGF1R/4667 |
| Applications: | Flow, ICC/IF, MA |
![Protein Array: IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free [NBP3-14094]](https://resources.rndsystems.com/images/products/IGF-I-R-IGF1R-Antibody-IGF1R-4667-Azide-and-BSA-Free-Protein-Array-NBP3-14094-img0001.jpg "Protein Array: IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free [NBP3-14094]")
IGF1R inhibitor
| Chemical Name: | N-(5-Chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)urea |
| Purity: | ≥98% |
Dual IR/IGF1R inhibitor
| Chemical Name: | 4-[[(2S)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-3-[7-methyl-5-(4-morpholinyl)-1H-benzimidazol-2-yl]-2(1H)-pyridinone |
| Purity: | ≥98% |
Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK)
| Chemical Name: | 2-[[2-[[1-[(Dimethylamino)ethanoyl]-5-(methyloxy)-2,3-dihydro-1H-indol-6-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-6-fluoro-N-methylbenzamide |
| Purity: | ≥98% |
