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3 results for "NAMPT Inhibitors" in 产品
NAMPT Inhibitors
Nicotinamide phosphoribosyltransferase (NAMPT), EC 2.4.2.12, is an enzyme that catalyzes the transfer of a phosphoribosyl group to nicotinamide (NAM), forming nicotinamide mononucleotide (NMN), which is then converted to nicotinamide adenine dinucleotide (NAD). The formation of NMN is the rate limiting step for the synthesis of NAD, an important intermediate of cell metabolism and redox reactions. Next NAD-dependent enzymes, such as poly (ADP-ribose) polymerase (PARP) and sirtuins, catalyze ...
NAMPT inhibitor; also GLUT1 inhibitor
| Chemical Name: | 4-[[[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinylbenzamide |
| Purity: | ≥98% |
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NAMPT inhibitor; active in vivo and cytotoxic
| Chemical Name: | N-[6-(4-Chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinylguanidine |
| Purity: | ≥98% |
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Potent and non-competitive NAMPT inhibitor; induces apoptosis and autophagy
| Chemical Name: | (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide |
| Purity: | ≥98% |
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