Protein-synthesizing GTPase Compounds

Translational GTPases (EC 3.6.5.3) facilitate and control the process of protein synthesis from RNA, through translation. This protein family contains initiation factors and elongation factors, which are found in both prokaryotes and eukaryotes.

Initiation factors (IFs) are involved in the first phase of translation; in prokaryotes these are named PIF1-3, while in eukaryotes there are at least 12 IFs and each is composed of multiple polypeptides. Eukaryotic IFs (eIFs) each have a slightly ...