14 results for "RNA/DNA Polymerase Inhibitors" in 产品
RNA/DNA Polymerase Inhibitors
DNA polymerases cannot initiate de novo DNA synthesis; they require a primer, formed by the enzyme primase. DNA polymerases are unidirectional and can only elongate DNA chains in a 5' to 3' direction. A unique feature of some of these enzymes is their 'proofreading' ability. DNA polymerases I, II and III have 3' to 5' exonuclease activity and they can remove incorrectly newly incorporated nucleotides. This makes the error rate during DNA replication very low, hence maintaining the integrity of the genome.
Inhibits RNA polymerase
| Chemical Name: | 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
| Purity: | ≥95% |
Inhibitor of DNA and RNA polymerase
| Chemical Name: | (1S)-5-Deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1.fwdarw.3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1.fwdarw.3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose |
| Purity: | ≥95% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug
| Alternate Names: | GS-5734 |
| Chemical Name: | 2-Ethylbutyl (2S)-2-[[(S)-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate |
| Purity: | ≥98% |
Reverse transcriptase inhibitor
| Alternate Names: | PMPA,(R)-9-(2-Phosphonoylmethoxypropyl)adenine |
| Chemical Name: | (R)-[[2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid |
| Purity: | ≥98% |
DNA polymerase α, δ and ε inhibitor
| Chemical Name: | (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol |
| Purity: | ≥98% |
Inhibitor of RNA polymerase II
| Chemical Name: | cyclo[L-Asparaginyl-4-hydroxy-L-prolyl-(R)-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic (4→8)-sulfide (R)-S-oxide |
| Purity: | ≥95% |
RNA polymerase I inhibitor; also p53 pathway activator
| Chemical Name: | N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide |
| Purity: | ≥98% |
Potent and selective hepatitis B virus inhibitor
| Alternate Names: | BMS 200475,SQ 34676 |
| Chemical Name: | 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one |
| Purity: | ≥98% |
Viral RNA polymerase inhibitor
| Alternate Names: | T 705 |
| Chemical Name: | 6-Fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide
| Chemical Name: | (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral
| Alternate Names: | BCX 4430 |
| Chemical Name: | (2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3,4-pyrrolidinediol dihydrochloride |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleoside
| Chemical Name: | N-Hydroxycytidine |
| Purity: | ≥98% |
RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika
| Chemical Name: | (2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2H-benzo[a]quinolizine dihydrochloride |
| Purity: | ≥98% |
Non-nucleoside reverse transcriptase inhibitor
| Chemical Name: | 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile |
| Purity: | ≥98% |
