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4 results for "Sigma1 Receptor Ligands Small Molecules and Peptides" in 产品
Sigma1 Receptor Ligands Small Molecules and Peptides
σ1 receptors are members of the σ family of receptors that also includes σ2 receptors. Originally thought to be opioid receptors or the phencyclidine binding site on the NMDA receptor, they are now known to be distinct targets. These receptors are distinguished from σ2 receptors as they exhibit high affinity and stereoselectivity for the (+)-isomers of pentazocine, SK&F 10047 and cyclazocine, as well as having different tissue distribution patterns and subcellular ...
Dopamine antagonist; displays some D2 selectivity
| Chemical Name: | 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone hydrochloride |
| Purity: | ≥98% |
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Selective σ1 ligand, putative antagonist
| Chemical Name: | 1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine dihydrochloride |
| Purity: | ≥99% |
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5-HT reuptake inhibitor
| Chemical Name: | (E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate |
| Purity: | ≥99% |
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Selective σ1 ligand; antidepressant
| Chemical Name: | (R)-(+)-N-Cyclopropylmethyl-α-ethyl-N-methyl-α-[(2E)-3-phenyl-2-propenyl)benzenemethanamine hydrochloride |
| Purity: | ≥98% |
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