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TANK Binding Kinase Controls Small Molecules and Peptides

TANK binding kinase (TBK) EC 2.7.11.1 is a ubiquitously expressed serine/threonine kinase belonging to the IκB Kinase (IKK) family, which regulates NF-κB signaling. This kinase has a range of substrates, leading to involvement in multiple pathways including immune response and inflammation, autophagy, cell proliferation and growth and insulin signaling.

TBK has a critical role in innate immunity and inflammation and functions downstream of multiple interferon (IFN) inducing pathways ...

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TBK1 control PROTAC® 4

Catalog #: 7260
Citations (3)
Product Documents

Negative control for TBK1 PROTAC® 3i (Cat. No. 7259)

Chemical Name: (2S,4S)-1-((S)-18-(4-((5-Bromo-4-((3-(N-methylcyclobutanecarboxamido)propyl)amino)pyrimidin-2-yl)amino)phenoxy)-2-(tert-butyl)-4-oxo-6,10,15-trioxa-3-azaoctadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98%
Negative control for TBK1 PROTAC® 3i (Cat. No. 7259)
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