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2 results for "TR alpha/NR1A1 Small Molecules and Peptides" in 产品
TR alpha/NR1A1 Small Molecules and Peptides
Thyroid hormone Receptor alpha (TR alpha, THRA; NR1A1) is a member of the nuclear hormone receptor superfamily. The ligands for TR alpha are the thyroid hormones, which exist in two forms: T4 (3,5,3,5-tetraiodo-L-thyronine) and T3 (3,5,3-tri-iodo-L-thyronine). TR alpha plays a critical role in the differentiation, growth, metabolism and physiology of a wide variety of tissues. The major partners of TRs are the RXRs, which strongly enhance their ability to bind to specific DNA sequences and contribute to the specificity of TR.
High affinity thyroid receptor α (TRα) and TRβ agonist; thyromimetic
| Alternate Names: | Sobetirome |
| Chemical Name: | 2-[4-[[4-Hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]acetic acid |
| Purity: | ≥98% |
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Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
| Chemical Name: | O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine |
| Purity: | ≥98% |
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