2 results for "TR beta 1/NR1A2 Small Molecules and Peptides" in 产品

TR beta 1/NR1A2 Small Molecules and Peptides

Thyroid Hormone Receptor beta is encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Defects in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH).

Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells

Chemical Name: O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
Purity: ≥98%
Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
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High affinity thyroid receptor α (TRα) and TRβ agonist; thyromimetic

Alternate Names: Sobetirome
Chemical Name: 2-[4-[[4-Hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]acetic acid
Purity: ≥98%
High affinity thyroid receptor α (TRα) and TRβ agonist; thyromimetic
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