2 results for "Ubiquitin E3 Ligase Antagonists Small Molecules and Peptides" in 产品

Ubiquitin E3 Ligase Antagonists Small Molecules and Peptides

Ubiquitin E3 ligases (EC 6.3.2.19) attach ubiquitin molecules onto lysine residues of proteins in order to target the protein for a specific cellular process, such as proteasomal degradation or an alteration in subcellular localization. In addition to the specific ubiquitin ligases such as MDM2, E3A and anaphase-promoting complex (APC), many other proteins also contain domains that possess ubiquitin ligase activity. Almost all known ubiquitin E3 ligases contain one of three domains: a HECT, ...

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Selective GID4 antagonist

Chemical Name: N-((1s,4s)-4-(1H-Benzo[d]imidazol-2-yl)cyclohexyl)-2-(((1H-indol-2-yl)methyl)amino)acetamide dihydrochloride
Purity: ≥98%
GID4 antagonist
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Monovalent IAP antagonist

Chemical Name: (2S,4S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-4-phenoxy-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)pyrrolidine-2-carboxamide
Purity: ≥97%
Selective cIAP1 Degrader (PROTAC®)
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