2 results for "Voltage-gated Potassium Channel Blockers" in 产品

Voltage-gated Potassium Channel Blockers

Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The pore-forming α-subunits contain a single pore-forming region and combine to form tetramers. Heteromeric channels can be formed within subfamilies e.g. KV1.1 with KV1.2 and KCNQ2 with KCNQ3.

H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker

Chemical Name: α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
Purity: ≥98%
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker
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Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker

Alternate Names: Hismanal
Chemical Name: 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine
Purity: ≥98%
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker
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