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21 results for "Voltage-gated Sodium Channel Blockers" in 产品

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Voltage-gated Sodium Channel Blockers

Voltage-gated sodium channels (Na_V) are responsible for action potential initiation and propagation in excitable cells, including nerve, muscle, and neuroendocrine cell types. They are also expressed at low levels in non-excitable cells, where their physiological role is unclear.

Structurally, Na_V channels are composed of one pore-forming α-subunit, which may be associated with either one or more β-subunits. α-subunits are composed of four homologous domains, each of which contains six transmembrane segments. The fourth transmembrane loop (S4) acts as the 'voltage sensor' and is activated by changes in membrane potential. S4 is also involved in channel gating.

Tetrodotoxin

Catalog #: 1078

(5)

Alternate Names:	TTx
Chemical Name:	(4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol
Purity:	≥98%

Alternate Names:	TTx citrate
Chemical Name:	(4R,4aR,5R,7S,9S,10S,10aR,11S,12S)-Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pentol citrate
Purity:	≥98%

Chemical Name:	N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium chloride
Purity:	≥98%

Chemical Name:	2-Amino-6-trifluoromethoxybenzothiazole hydrochloride
Purity:	≥98%

Chemical Name:	3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride
Purity:	≥98%

Chemical Name:	5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furancarboxamide
Purity:	≥98%

Chemical Name:	N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate
Purity:	≥98%

Alternate Names:	Ko 1173
Chemical Name:	1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride
Purity:	≥98%

Chemical Name:	N-[2-Methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide
Purity:	≥98%

Chemical Name:	2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Purity:	≥98%

Chemical Name:	5-(4-Butoxy-3-chlorophenyl)-N-[[2-(4-morpholinyl)-3-pyridinyl]methyl-3-pyridine carboxamide
Purity:	≥97%

Alternate Names:	619C89
Chemical Name:	2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine
Purity:	≥98%

Chemical Name:	α-Phenyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]benzeneacetamide
Purity:	≥98%

Chemical Name:	4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate
Purity:	≥98%

Chemical Name:	1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine
Purity:	≥98%

Chemical Name:	4-[[1-[[2-Chloro-5-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methoxy]-5-cyclopropyl-2-fluoro-N-(methylsulfonyl)benzamide
Purity:	≥98%

Voltage-gated Sodium Channel Blockers

Tetrodotoxin

Tetrodotoxin citrate

QX 314 chloride

QX 314 bromide

Riluzole hydrochloride

Amiloride hydrochloride

A 803467

Flecainide acetate

Mexiletine hydrochloride

TC-N 1752

APETx2

Lidocaine

ProTx II

Sipatrigine

Jingzhaotoxin III

ICA 121431

PF 05089771

OD1

A 887826

PF 04885614

GX 201