2-Chloroadenosine

Key Product Details

Product Description

2-Chloroadenosine is a metabolically stable analog of adenosine that behaves as an adenosine receptor agonist (K_i values are 300, 80 and 1900 nM for A₁, A_2A and A₃ receptors respectively). Anticonvulsive in vivo.

Product Specifications for 2-Chloroadenosine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for 2-Chloroadenosine

The following data is based on the product molecular weight 301.69.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.31 mL	16.57 mL	33.15 mL
5 mM	0.66 mL	3.31 mL	6.63 mL
10 mM	0.33 mL	1.66 mL	3.31 mL
50 mM	0.07 mL	0.33 mL	0.66 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 30 publications citing the usage of this product.

• Pourgholami Intra-amygdala infusion of 2-chloroadenosine suppresses amygdala-kindled seizures. Brain Res. 1997 PMID: 9439826
• Abdul-Ghani The protective effect of 2-chloroadenosine against the development of amygdala kindling and on amygdala-kindled seizures. Eur.J.Pharmacol. 1997 PMID: 9178649
• Mathot Pharmacokinetic-haemodynamic relationships of 2-chloroadenosine at adenosine A₁ and A_2a receptors in vivo. Br.J.Pharmacol. 1996 PMID: 8735640

Product Documents for 2-Chloroadenosine