Chemical Name: 6-Amino-2-chloropurine riboside
Biological Activity2-Chloroadenosine is a metabolically stable analog of adenosine that behaves as an adenosine receptor agonist (Ki values are 300, 80 and 1900 nM for A1, A2A and A3 receptors respectively). Anticonvulsive in vivo.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Pharmacokinetic-haemodynamic relationships of 2-chloroadenosine at adenosine A1 and A2a receptors in vivo.
Mathot et al.
Intra-amygdala infusion of 2-chloroadenosine suppresses amygdala-kindled seizures.
Pourgholami et al.
Brain Res., 1997;775:37
The protective effect of 2-chloroadenosine against the development of amygdala kindling and on amygdala-kindled seizures.
Abdul-Ghani et al.
Citation for 2-Chloroadenosine
The citations listed below are publications that use Tocris products. Selected citations for 2-Chloroadenosine include:
1 Citation: Showing 1 - 1
The A2aR adenosine receptor controls cytokine production in iNKT cells.
Authors: Nowak Et al.
Front Cell Neurosci 2010;40:682
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