Catalog Number: 3136
Alternate Names: 2-CADO
Chemical Name: 6-Amino-2-chloropurine riboside
Biological Activity
Metabolically stable analog of adenosine that behaves as an adenosine receptor agonist (Ki values are 300, 80 and 1900 nM for A1, A2A and A3 receptors respectively). Anticonvulsive in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 25 mM in water and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Intra-amygdala infusion of 2-chloroadenosine suppresses amygdala-kindled seizures.
    Pourgholami et al.
    Brain Res., 1997;775:37
  2. The protective effect of 2-chloroadenosine against the development of amygdala kindling and on amygdala-kindled seizures.
    Abdul-Ghani et al.
    Eur.J.Pharmacol., 1997;326:7
  3. Pharmacokinetic-haemodynamic relationships of 2-chloroadenosine at adenosine A1 and A2a receptors in vivo.
    Mathot et al.
    Br.J.Pharmacol., 1996;118:369

The citations listed below are publications that use Tocris products. Selected citations for 2-Chloroadenosine include:

Showing Results 1 - 1 of 1

  1. The A2aR adenosine receptor controls cytokine production in iNKT cells.
    Authors: Nowak Et al.
    Front Cell Neurosci
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