Catalog Number: 0245
Chemical Name: (RS)-3-Amino-2-(4-chlorophenyl)-2-hydroxypropyl-sulfonic acid
Biological Activity
Selective antagonist at GABAB receptors.
Technical Data
  • M.Wt:
    265.71
  • Formula:
    C9H12ClNO4S
  • Solubility:
    Soluble to 5 mM in water and to 100 mM in 1eq. NaOH
  • Storage:
    Store at RT
  • CAS No:
    117354-64-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Baclofen antagonism by 2-hydroxysaclofen in the cat spinal cord.
    Curtis et al.
    Neurosci.Lett., 1988;92:97
  2. 2-Hydroxysaclofen: an improved antagonist at central and peripheral GABAB receptors.
    Kerr et al.
    Neurosci.Lett., 1988;92:92
Citations:

The citations listed below are publications that use Tocris products. Selected citations for 2-Hydroxysaclofen include:

2 Citations: Showing 1 - 2
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  1. Peripheral GABAB agonists stimulate gastric acid secretion in mice.
    Authors: Piqueras and Martínez
    Br J Pharmacol 2004;142:1038
  2. Physiological contribution of the astrocytic environment of neurons to intersynaptic crosstalk.
    Authors: Piet Et al.
    Nature 2004;101:2151
Tocris Small Molecules
Description Application Cat# Citations Images  

Saclofen

0246 9  
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