Catalog Number: 1062
Alternate Names: 2-Methylthio-ATP
Chemical Name: 2-Methylthioadenosine-5'-triphosphate tetrasodium salt
Biological Activity
P2 purinoceptor agonist.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Specific but non-competitive inhibition by 2-alkylthioanalogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate.
    Cusack et al.
    Br.J.Pharmacol., 1982;75:397
  2. Studies on the stereoselectivity of the P2-purinoreceptor.
    Burnstock et al.
    Br.J.Pharmacol., 1983;79:907
  3. Purinoceptor subtypes mediating contraction and relaxation of marmoset urinary bladder smooth muscle.
    McMurray et al.
    Br.J.Pharmacol., 1998;123:1579
  4. International Union of Pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits.
    Khakh et al.
    Pharmacol.Rev., 2001;53:107

The citations listed below are publications that use Tocris products. Selected citations for 2-Methylthioadenosine triphosphate tetrasodium salt include:

2 Citations: Showing 1 - 2
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  1. Purinergic and Cholinergic Drugs Mediate Hyperventilation in Zebrafish: Evidence from a Novel Chemical Screen.
    Authors: Rahbar Et al.
    Nature 2016;11:e0154261
  2. Agonist-bound structure of the human P2Y12 receptor.
    Authors: Zhang Et al.
    Med J Islam Repub Iran 2014;509:119

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