Human P2X1/P2RX1 (NP_002549) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Human P2X1/P2RX1 (NP_002549) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: P2X1/P2RX1

Biologic responses to ATP, ADP, and other extracellular nucleotides are mediated by P2-nucleotide receptors belonging to 2 major classes: G protein-coupled P2Y receptors and nucleotide-gated ion channel P2X receptors. P2RX1 functions as a ligand-gated ion channel with relatively high calcium permeability. Mouse studies suggest that this receptor is essential for normal male reproductive function. The development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.

Long Name
P2X Purinergic Receptor 1
Entrez Gene IDs
5023 (Human); 25505 (Rat)
Alternate Names
ATP receptor; P2RX1; P2X purinoceptor 1; P2X receptor, subunit 1; P2X1; P2X1P2X1 receptor; P2XMR; purinergic receptor P2X, ligand-gated ion channel, 1; Purinergic receptor


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