Biologic responses to ATP, ADP, and other extracellular nucleotides are mediated by P2-nucleotide receptors belonging to 2 major classes: G protein-coupled P2Y receptors and nucleotide-gated ion channel P2X receptors. P2RX1 functions as a ligand-gated ion channel with relatively high calcium permeability. Mouse studies suggest that this receptor is essential for normal male reproductive function. The development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Human P2X1/P2RX1 (NP_002549) VersaClone cDNA
R&D Systems | Catalog # RDC0513
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: P2X1/P2RX1
Long Name
P2X Purinergic Receptor 1
Alternate Names
P2RX1, P2XMR
Gene Symbol
P2RX1
UniProt
Additional P2X1/P2RX1 Products
Product Documents for Human P2X1/P2RX1 (NP_002549) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human P2X1/P2RX1 (NP_002549) VersaClone cDNA
For research use only
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